FTPase 저해활성 : 1-아자안트라퀴논 유도체
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- Title
- FTPase 저해활성 : 1-아자안트라퀴논 유도체
- Author(s)
- Hee Soon Lee; Seung Ho Lee; Seoung Soo Hong; Ji Youn Nam; Byoung-Mog Kwon
- Bibliographic Citation
- Chungbuk Jurnal of Pharmaceutical Sciences, vol. 13, pp. 71-78
- Publication Year
- 1998
- Abstract
- Inhibitory activity of twenty four 3- or 4- substituted - I - azaanthraquinones were studied on Farnesyl protein transferase (FPTase) and Srchomology 2 domain (SH2) binding. The most activi compound 16 showed 76.7% inhibition on FPTase at 100μg/ml and 64.4% inhibition of SH2 at 50μg/ml.
- ISSN
- I000-0115
- Publisher
- Korea Soc-Assoc-Inst
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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