DC Field | Value | Language |
---|---|---|
dc.contributor.author | Im Seon Lee | - |
dc.contributor.author | Keun Young Jung | - |
dc.contributor.author | Sei Ryang Oh | - |
dc.contributor.author | Si Hyung Park | - |
dc.contributor.author | Kyung Seop Ahn | - |
dc.contributor.author | Hyeong Kyu Lee | - |
dc.date.accessioned | 2017-04-19T08:55:59Z | - |
dc.date.available | 2017-04-19T08:55:59Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 0918-6158 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/4679 | - |
dc.description.abstract | We studied the structure-activity relationships of lignans from Schisandra chinensis and their derivatives as platelet activating factor (PAF) antagonists. Strong activity was shown in lignans without an ester group at C-6, a hydroxyl group at C-7 or a methylene dioxy moiety and with an R-biphenyl configuration. 6(7)-Dehydroschisandrol A, a derivative of schisandrol A, showed the highest activity (IC50, 2.1 x 10-6 M) in this study. | - |
dc.publisher | Pharmaceutical Soc Japan | - |
dc.title | Structure-activity relationships of lignans from Schisandra chinensis as platelet activating factor antagonists | - |
dc.title.alternative | Structure-activity relationships of lignans from Schisandra chinensis as platelet activating factor antagonists | - |
dc.type | Article | - |
dc.citation.title | Biological & Pharmaceutical Bulletin | - |
dc.citation.number | 3 | - |
dc.citation.endPage | 267 | - |
dc.citation.startPage | 265 | - |
dc.citation.volume | 22 | - |
dc.contributor.affiliatedAuthor | Im Seon Lee | - |
dc.contributor.affiliatedAuthor | Keun Young Jung | - |
dc.contributor.affiliatedAuthor | Sei Ryang Oh | - |
dc.contributor.affiliatedAuthor | Si Hyung Park | - |
dc.contributor.affiliatedAuthor | Kyung Seop Ahn | - |
dc.contributor.affiliatedAuthor | Hyeong Kyu Lee | - |
dc.contributor.alternativeName | 이임선 | - |
dc.contributor.alternativeName | 정근영 | - |
dc.contributor.alternativeName | 오세량 | - |
dc.contributor.alternativeName | 박시형 | - |
dc.contributor.alternativeName | 안경섭 | - |
dc.contributor.alternativeName | 이형규 | - |
dc.identifier.bibliographicCitation | Biological & Pharmaceutical Bulletin, vol. 22, no. 3, pp. 265-267 | - |
dc.identifier.doi | 10.1248/bpb.22.265 | - |
dc.subject.keyword | Schisandra chinensis | - |
dc.subject.keyword | platelet activating factor antagonist | - |
dc.subject.keyword | dibenzocyclooctadiene | - |
dc.subject.keyword | lignan | - |
dc.subject.local | Schisandra chinensis | - |
dc.subject.local | platelet activating factor antagonist | - |
dc.subject.local | dibenzocyclooctadiene | - |
dc.subject.local | lignan | - |
dc.subject.local | Lignans | - |
dc.subject.local | Lignan | - |
dc.subject.local | lignans | - |
dc.description.journalClass | Y | - |
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