PAC and cosmid contig spanning the HOXA cluster on human chromosome 7p15

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dc.contributor.authorMyoung Hee Kim-
dc.contributor.authorJong Hoon Park-
dc.contributor.authorHyoung Woo Park-
dc.contributor.authorIn Hyuk Chung-
dc.contributor.authorKyung Ah Park-
dc.date.accessioned2017-04-19T08:56:23Z-
dc.date.available2017-04-19T08:56:23Z-
dc.date.issued1998-
dc.identifier.issn0740-7750-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4830-
dc.description.abstractTo construct the PAC and cosmid contig map spanning the HOXA cluster on human chromosome 7, we used 9 DNA markers (D7S2243, D7S3010, HOXA1, EVX1, 750, pBH8, p60, p8.0, and HOXA11), among which the final 4 were generated in this study by shotgun cloning strategy. From the libraries, 5 PAC and 35 cosmid clones were screened and as a result, an overlapping continuous array of cosmid and PAC clones covering the genomic region (about 200 kb) spanning the entire cluster were constructed. The isolated cosmids contained several consecutive HOX genes of regional group, probably sharing the regulatory processes such as alternative splicing or polyadenylation, and thus could be used as useful materials for elucidating the molecular mechanism of HOX gene expression in the future.-
dc.titlePAC and cosmid contig spanning the HOXA cluster on human chromosome 7p15-
dc.title.alternativePAC and cosmid contig spanning the HOXA cluster on human chromosome 7p15-
dc.typeArticle-
dc.citation.titleSomatic Cell and Molecular Genetics-
dc.citation.number4-
dc.citation.endPage248-
dc.citation.startPage245-
dc.citation.volume24-
dc.contributor.affiliatedAuthorJong Hoon Park-
dc.contributor.alternativeName김명희-
dc.contributor.alternativeName박종훈-
dc.contributor.alternativeName박형우-
dc.contributor.alternativeName정인혁-
dc.contributor.alternativeName박경아-
dc.identifier.bibliographicCitationSomatic Cell and Molecular Genetics, vol. 24, no. 4, pp. 245-248-
dc.identifier.doi10.1023/B:SCAM.0000007126.79352.18-
dc.description.journalClassN-
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