PAC and cosmid contig spanning the HOXA cluster on human chromosome 7p15

Cited 3 time in scopus
Metadata Downloads
Title
PAC and cosmid contig spanning the HOXA cluster on human chromosome 7p15
Author(s)
Myoung Hee Kim; Jong Hoon Park; Hyoung Woo Park; In Hyuk Chung; Kyung Ah Park
Bibliographic Citation
Somatic Cell and Molecular Genetics, vol. 24, no. 4, pp. 245-248
Publication Year
1998
Abstract
To construct the PAC and cosmid contig map spanning the HOXA cluster on human chromosome 7, we used 9 DNA markers (D7S2243, D7S3010, HOXA1, EVX1, 750, pBH8, p60, p8.0, and HOXA11), among which the final 4 were generated in this study by shotgun cloning strategy. From the libraries, 5 PAC and 35 cosmid clones were screened and as a result, an overlapping continuous array of cosmid and PAC clones covering the genomic region (about 200 kb) spanning the entire cluster were constructed. The isolated cosmids contained several consecutive HOX genes of regional group, probably sharing the regulatory processes such as alternative splicing or polyadenylation, and thus could be used as useful materials for elucidating the molecular mechanism of HOX gene expression in the future.
ISSN
0740-7750
DOI
http://dx.doi.org/10.1023/B:SCAM.0000007126.79352.18
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.