Gene expression of neuroD/BETA2 during development of the mouse central nervous system = 생쥐 중추신경계에서 NeuroD/BETA2 유전자의 발현

Cited 0 time in scopus
Metadata Downloads
Title
Gene expression of neuroD/BETA2 during development of the mouse central nervous system = 생쥐 중추신경계에서 NeuroD/BETA2 유전자의 발현
Author(s)
Jang Hyeon Cho; Woo Sup Hwang; Yeon Soo Kim; Young Don Lee; Hae Young Suh-Kim
Bibliographic Citation
Korean Journal of Anatomy, vol. 33, no. 1, pp. 13-19
Publication Year
2000
Abstract
NeuroD/BETA2, a basic helix-loop-helix transcription factor, has been known to play a role in terminal differentiation during neurogenesis. To gain further insight into the function of NeuroD/BETA2 in the nervous system development, we examined the expression pattern of NeuroD/BETA2 during embryonic and postnatal development by in situ hybridization. Dynamic changes of NeuroD/BETA2 expression were observed in the developing nervous system. Gene expression of the NeuroD/BETA2 in developing cerebellum and hippocampus increased during the embryonic stages and persisted throughout postnatal development and remained at a stable level in the adult brain. NeuroD/BETA2 expression was detected in postmitotic cells in the subventricular zone of the cerebrum during embryogenesis. This observation confirms that NeuroD/BETA2 may have a role in terminal differentiation during neurogenesis.
Keyword
neuroDBETA2brainmouse
ISSN
1225-1305
Publisher
South Korea
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.