Two new constituents of isodon excisus and their evaluation in an apoptosis inhibition assay

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Title
Two new constituents of isodon excisus and their evaluation in an apoptosis inhibition assay
Author(s)
Choong Hwan Lee; Jin Hee Kim; Ho Jae Lee; Sang Myung Lee; Yung Hee Kho
Bibliographic Citation
Journal of Natural Products, vol. 64, no. 5, pp. 659-660
Publication Year
2001
Abstract
Investigation of the whole plant of Isodon excisus resulted in the isolation of two new apoptosis inhibitors (1 and 2). Compounds 1 and 2 inhibited etoposide-induced apoptosis in U937 cells with IC50 values of 10.2 and 52.4 μg/mL, respectively. The structures of 1 and 2 were determined by spectral data interpretation.
ISSN
0163-3864
Publisher
Amer Chem Soc
DOI
http://dx.doi.org/10.1021/np000604g
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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