Two new constituents of isodon excisus and their evaluation in an apoptosis inhibition assay
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- Title
- Two new constituents of isodon excisus and their evaluation in an apoptosis inhibition assay
- Author(s)
- Choong Hwan Lee; Jin Hee Kim; Ho Jae Lee; Sang Myung Lee; Yung Hee Kho
- Bibliographic Citation
- Journal of Natural Products, vol. 64, no. 5, pp. 659-660
- Publication Year
- 2001
- Abstract
- Investigation of the whole plant of Isodon excisus resulted in the isolation of two new apoptosis inhibitors (1 and 2). Compounds 1 and 2 inhibited etoposide-induced apoptosis in U937 cells with IC50 values of 10.2 and 52.4 μg/mL, respectively. The structures of 1 and 2 were determined by spectral data interpretation.
- ISSN
- 0163-3864
- Publisher
- Amer Chem Soc
- Full Text Link
- http://dx.doi.org/10.1021/np000604g
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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