Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor γ
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- Title
- Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor γ
- Author(s)
- Bang Yeon Hwang; Jeong Hyung Lee; Jeong Bum Nam; Hang Sub Kim; Young Soo Hong; Jung Joon Lee
- Bibliographic Citation
- Journal of Natural Products, vol. 65, no. 4, pp. 616-617
- Publication Year
- 2002
- Abstract
- Two new acyclic furanoditerpene compounds, saurufuran A (1) and B (2), were obtained from the root of Saururus chinensis, and their structures were elucidated by means of 1D and 2D NMR spectroscopic analyses. Saurufuran A (1) is effective on the activation of peroxisome proliferator-activated receptor γ (PPARγ) with an EC50 value of 16.7 μM; however, saurufuran B (2), with an EC50 value of > 100 μM, weakly activated the PPARγ.
- ISSN
- 0163-3864
- Publisher
- Amer Chem Soc
- Full Text Link
- http://dx.doi.org/10.1021/np010440j
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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