Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor γ

Cited 56 time in scopus
Metadata Downloads
Title
Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor γ
Author(s)
Bang Yeon Hwang; Jeong Hyung Lee; Jeong Bum Nam; Hang Sub Kim; Young Soo Hong; Jung Joon Lee
Bibliographic Citation
Journal of Natural Products, vol. 65, no. 4, pp. 616-617
Publication Year
2002
Abstract
Two new acyclic furanoditerpene compounds, saurufuran A (1) and B (2), were obtained from the root of Saururus chinensis, and their structures were elucidated by means of 1D and 2D NMR spectroscopic analyses. Saurufuran A (1) is effective on the activation of peroxisome proliferator-activated receptor γ (PPARγ) with an EC50 value of 16.7 μM; however, saurufuran B (2), with an EC50 value of > 100 μM, weakly activated the PPARγ.
ISSN
0163-3864
Publisher
Amer Chem Soc
DOI
http://dx.doi.org/10.1021/np010440j
Type
Article
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.