Novel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors

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dc.contributor.authorL Toma-
dc.contributor.authorM P Giovannoni-
dc.contributor.authorC Vergelli-
dc.contributor.authorV D Piaz-
dc.contributor.authorByoung-Mog Kwon-
dc.contributor.authorYoung Kook Kim-
dc.contributor.authorA Gelain-
dc.contributor.authorD Barlocco-
dc.date.accessioned2017-04-19T08:59:47Z-
dc.date.available2017-04-19T08:59:47Z-
dc.date.issued2002-
dc.identifier.issn0365-6233-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6091-
dc.description.abstractA new series of pyridazine derivatives, structurally related to the previously reported ACAT inhibitors 3-(cyclo)alkylamino-5,6-diphenyl-pyridazines, were synthesized and tested for their inhibitory properties. Substitution of the 3-alkylamino chain with a phenylamino group maintains activity. In contrast, the presence of either substituents on the phenylamino group or aliphatic rings having more or less than six carbon atoms lowers it.-
dc.publisherWiley-
dc.titleNovel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors-
dc.title.alternativeNovel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors-
dc.typeArticle-
dc.citation.titleArchiv der Pharmazie-
dc.citation.number11-
dc.citation.endPage566-
dc.citation.startPage563-
dc.citation.volume335-
dc.contributor.affiliatedAuthorByoung-Mog Kwon-
dc.contributor.affiliatedAuthorYoung Kook Kim-
dc.contributor.alternativeNameToma-
dc.contributor.alternativeNameGiovannoni-
dc.contributor.alternativeNameVergelli-
dc.contributor.alternativeNamePiaz-
dc.contributor.alternativeName권병목-
dc.contributor.alternativeName김영국-
dc.contributor.alternativeNameGelain-
dc.contributor.alternativeNameBarlocco-
dc.identifier.bibliographicCitationArchiv der Pharmazie, vol. 335, no. 11, pp. 563-566-
dc.identifier.doi10.1002/ardp.200290010-
dc.subject.keyword5,6-Diphenylpyridazine derivatives-
dc.subject.keywordACAT inhibitors-
dc.subject.keywordAcyl-CoA:cholesterol acyltransferase (ACAT)-
dc.subject.keywordHypercholesterolemia-
dc.subject.local5,6-Diphenylpyridazine derivatives-
dc.subject.localACAT inhibitor-
dc.subject.localACAT inhibitors-
dc.subject.localACAT (acyl-CoA: cholesterol acyltransferase)-
dc.subject.localAcyl-CoA:cholesterol acyltransferase (ACAT)-
dc.subject.localcholesterol acytransferase (ACAT)-
dc.subject.localCholestrol Acyl Transferase (ACAT)-
dc.subject.localAcyl CoA: cholesterol acyltransferase (ACAT)-
dc.subject.localACAT (Acyl-CoA:cholesterol acyltransferase)-
dc.subject.localAcyl-CoA:cholesterol acyltransferase-
dc.subject.localACAT-
dc.subject.localAcyl-CoA: cholesterol acyltransferase-
dc.subject.localacyl-CoA:cholesterol acyltransferase (ACAT)-
dc.subject.localAcyl-CoA: cholesterol acyltransferase (ACAT)-
dc.subject.localAcyl-coenzyme A: cholesterol acyltransferase (ACAT)-
dc.subject.localCholesterol acytransferase (ACAT)-
dc.subject.localcholestrol acyl transferase (ACAT)-
dc.subject.localHypercholesterolemia-
dc.subject.localhypercholesterolemia-
dc.description.journalClassY-
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