Novel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | L Toma | - |
| dc.contributor.author | M P Giovannoni | - |
| dc.contributor.author | C Vergelli | - |
| dc.contributor.author | V D Piaz | - |
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.contributor.author | Young Kook Kim | - |
| dc.contributor.author | A Gelain | - |
| dc.contributor.author | D Barlocco | - |
| dc.date.accessioned | 2017-04-19T08:59:47Z | - |
| dc.date.available | 2017-04-19T08:59:47Z | - |
| dc.date.issued | 2002 | - |
| dc.identifier.issn | 0365-6233 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6091 | - |
| dc.description.abstract | A new series of pyridazine derivatives, structurally related to the previously reported ACAT inhibitors 3-(cyclo)alkylamino-5,6-diphenyl-pyridazines, were synthesized and tested for their inhibitory properties. Substitution of the 3-alkylamino chain with a phenylamino group maintains activity. In contrast, the presence of either substituents on the phenylamino group or aliphatic rings having more or less than six carbon atoms lowers it. | - |
| dc.publisher | Wiley | - |
| dc.title | Novel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors | - |
| dc.title.alternative | Novel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors | - |
| dc.type | Article | - |
| dc.citation.title | Archiv der Pharmazie | - |
| dc.citation.number | 11 | - |
| dc.citation.endPage | 566 | - |
| dc.citation.startPage | 563 | - |
| dc.citation.volume | 335 | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.affiliatedAuthor | Young Kook Kim | - |
| dc.contributor.alternativeName | Toma | - |
| dc.contributor.alternativeName | Giovannoni | - |
| dc.contributor.alternativeName | Vergelli | - |
| dc.contributor.alternativeName | Piaz | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.contributor.alternativeName | 김영국 | - |
| dc.contributor.alternativeName | Gelain | - |
| dc.contributor.alternativeName | Barlocco | - |
| dc.identifier.bibliographicCitation | Archiv der Pharmazie, vol. 335, no. 11, pp. 563-566 | - |
| dc.identifier.doi | 10.1002/ardp.200290010 | - |
| dc.subject.keyword | 5,6-Diphenylpyridazine derivatives | - |
| dc.subject.keyword | ACAT inhibitors | - |
| dc.subject.keyword | Acyl-CoA:cholesterol acyltransferase (ACAT) | - |
| dc.subject.keyword | Hypercholesterolemia | - |
| dc.subject.local | 5,6-Diphenylpyridazine derivatives | - |
| dc.subject.local | ACAT inhibitor | - |
| dc.subject.local | ACAT inhibitors | - |
| dc.subject.local | ACAT | - |
| dc.subject.local | ACAT (Acyl-CoA:cholesterol acyltransferase) | - |
| dc.subject.local | ACAT (acyl-CoA: cholesterol acyltransferase) | - |
| dc.subject.local | Acyl CoA: cholesterol acyltransferase (ACAT) | - |
| dc.subject.local | Acyl-CoA: cholesterol acyltransferase | - |
| dc.subject.local | Acyl-CoA: cholesterol acyltransferase (ACAT) | - |
| dc.subject.local | Acyl-CoA:cholesterol acyltransferase | - |
| dc.subject.local | Acyl-CoA:cholesterol acyltransferase (ACAT) | - |
| dc.subject.local | Acyl-coenzyme A: cholesterol acyltransferase (ACAT) | - |
| dc.subject.local | Cholesterol acytransferase (ACAT) | - |
| dc.subject.local | Cholestrol Acyl Transferase (ACAT) | - |
| dc.subject.local | acyl-CoA:cholesterol acyltransferase (ACAT) | - |
| dc.subject.local | cholesterol acytransferase (ACAT) | - |
| dc.subject.local | cholestrol acyl transferase (ACAT) | - |
| dc.subject.local | Hypercholesterolemia | - |
| dc.subject.local | hypercholesterolemia | - |
| dc.description.journalClass | Y | - |
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