Pheophorbide A-methyl ester, Acyl-CoA: cholesterol acyltransferase inhibitor from Diospyros kaki

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dc.contributor.authorMun Chual Rho-
dc.contributor.authorMi Yeon Chung-
dc.contributor.authorHye Young Song-
dc.contributor.authorOh Eok Kwon-
dc.contributor.authorSeung Woong Lee-
dc.contributor.authorJin Ah Baek-
dc.contributor.authorK H Jeune-
dc.contributor.authorKoanhoi Kim-
dc.contributor.authorHyun Sun Lee-
dc.contributor.authorYoung Kook Kim-
dc.date.accessioned2017-04-19T09:00:24Z-
dc.date.available2017-04-19T09:00:24Z-
dc.date.issued2003-
dc.identifier.issn0253-6269-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6273-
dc.description.abstractIn the course of our search for Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors from natural sources, a new type of ACAT inhibitor was isolated from a methanol extract of Diospyros kaki. On the basis of spectral and structural evidence, the compound was identified as pheophorbide A-methyl ester. Pheophorbide A-methyl ester inhibited ACAT activity in a dose dependent manner with an IC50 value of 1.85 μg/mL.-
dc.publisherPharmaceutical Soc Korea-
dc.titlePheophorbide A-methyl ester, Acyl-CoA: cholesterol acyltransferase inhibitor from Diospyros kaki-
dc.title.alternativePheophorbide A-methyl ester, Acyl-CoA: cholesterol acyltransferase inhibitor from Diospyros kaki-
dc.typeArticle-
dc.citation.titleArchives of Pharmacal Research-
dc.citation.number9-
dc.citation.endPage718-
dc.citation.startPage716-
dc.citation.volume26-
dc.contributor.affiliatedAuthorMun Chual Rho-
dc.contributor.affiliatedAuthorMi Yeon Chung-
dc.contributor.affiliatedAuthorHye Young Song-
dc.contributor.affiliatedAuthorOh Eok Kwon-
dc.contributor.affiliatedAuthorSeung Woong Lee-
dc.contributor.affiliatedAuthorJin Ah Baek-
dc.contributor.affiliatedAuthorKoanhoi Kim-
dc.contributor.affiliatedAuthorHyun Sun Lee-
dc.contributor.affiliatedAuthorYoung Kook Kim-
dc.contributor.alternativeName노문철-
dc.contributor.alternativeName정미연-
dc.contributor.alternativeName송혜영-
dc.contributor.alternativeName권오억-
dc.contributor.alternativeName이승웅-
dc.contributor.alternativeName백진아-
dc.contributor.alternativeName전경희-
dc.contributor.alternativeName김관회-
dc.contributor.alternativeName이현선-
dc.contributor.alternativeName김영국-
dc.identifier.bibliographicCitationArchives of Pharmacal Research, vol. 26, no. 9, pp. 716-718-
dc.identifier.doi10.1007/BF02976679-
dc.subject.keywordacyl-CoA-
dc.subject.keywordcholesterol acyltransferase-
dc.subject.keyworddiospyros kaki-
dc.subject.keywordpheophorbide A-methyl ester-
dc.subject.localacyl-CoA-
dc.subject.localAcyl-CoA-
dc.subject.localAcyl CoA-
dc.subject.localacyl CoA-
dc.subject.localcholesterol acyltransferase (ACAT)-
dc.subject.localCholesterol acyltransferase-
dc.subject.localCholesterol acyltransferase (ACAT)-
dc.subject.localcholesterol acyltransferase-
dc.subject.localDiospyros kaki-
dc.subject.localdiospyros kaki-
dc.subject.localpheophorbide A-methyl ester-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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