Lactones from the leaves of Litsea japonica and their anti-complement activity

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Title
Lactones from the leaves of Litsea japonica and their anti-complement activity
Author(s)
Byung Sun Min; Sun Young Lee; Jung Hee KimOk Kyoung Kwon; Bo Young Park; Ren Bo An; Joongku Lee; Hyung In Moon; Tae Jin Kim; Y H Kim; Hyouk Joung; Hyeong Kyu Lee
Bibliographic Citation
Journal of Natural Products, vol. 66, no. 10, pp. 1388-1390
Publication Year
2003
Abstract
Two new lactones, litsealactone A (1) and litsealactone B (2), were isolated from the leaves of Litsea japonica, together with three known lactones, hamabiwalactone A (3), hamabiwalactone B (4), and akolactone B (5). Hamabiwalactone B (4) and akolactone B (5) significantly inhibited complement activity in an in vitro anti-complement assay, with IC50 values of 149 and 58 μM, respectively.
ISSN
0163-3864
Publisher
Amer Chem Soc
DOI
http://dx.doi.org/10.1021/np030227i
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
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