Synthesis and cytotoxic activity of 1-(1-benzoylindoline-5-sulfonyl)-4-phenylimidazolidinones
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | S H Jung | - |
| dc.contributor.author | H S Lee | - |
| dc.contributor.author | N S Kim | - |
| dc.contributor.author | Hwan Mook Kim | - |
| dc.contributor.author | M S Lee | - |
| dc.contributor.author | D R Choi | - |
| dc.contributor.author | J A Lee | - |
| dc.contributor.author | Y H Chung | - |
| dc.contributor.author | Eun Yi Moon | - |
| dc.contributor.author | H S Hwang | - |
| dc.contributor.author | S K Seong | - |
| dc.contributor.author | D K Lee | - |
| dc.date.accessioned | 2017-04-19T09:01:11Z | - |
| dc.date.available | 2017-04-19T09:01:11Z | - |
| dc.date.issued | 2004 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6524 | - |
| dc.description.abstract | The novel 1-(1-benzoylindoline-5-sulfonyl)-4-phenyl-4,5-dihydroimidazolones 2 shows highly potent and broad cytotoxicities. Their cytotoxicities against human lung carcinoma A549, human chronic myelogenous leukemia K562, and human ovarian adenocarcinoma SK-OV-3 are compatible with doxorubicin. Compound 2p (1-[(4-aminobenzoyl)indoline-5-sulfonyl])-4-phenyl-4,5-dihydroimidazolone) exhibits a cytotoxicity that is far more potent than doxorubicin and also exhibits highly effective antitumour activities against murine (3LL, Colon 26) and human xenograft (NCI-H23, SW620) tumor models. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | Synthesis and cytotoxic activity of 1-(1-benzoylindoline-5-sulfonyl)-4-phenylimidazolidinones | - |
| dc.title.alternative | Synthesis and cytotoxic activity of 1-(1-benzoylindoline-5-sulfonyl)-4-phenylimidazolidinones | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 5 | - |
| dc.citation.endPage | 484 | - |
| dc.citation.startPage | 478 | - |
| dc.citation.volume | 27 | - |
| dc.contributor.affiliatedAuthor | Hwan Mook Kim | - |
| dc.contributor.affiliatedAuthor | Eun Yi Moon | - |
| dc.contributor.alternativeName | 정상헌 | - |
| dc.contributor.alternativeName | 이희순 | - |
| dc.contributor.alternativeName | 김남수 | - |
| dc.contributor.alternativeName | 김환묵 | - |
| dc.contributor.alternativeName | 이문선 | - |
| dc.contributor.alternativeName | 최동락 | - |
| dc.contributor.alternativeName | 이정아 | - |
| dc.contributor.alternativeName | 정용호 | - |
| dc.contributor.alternativeName | 문은이 | - |
| dc.contributor.alternativeName | 황현숙 | - |
| dc.contributor.alternativeName | 성승규 | - |
| dc.contributor.alternativeName | 이덕근 | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 27, no. 5, pp. 478-484 | - |
| dc.identifier.doi | 10.1007/BF02980119 | - |
| dc.subject.keyword | 1-(1-Benzoylindoline-5-sulfonyl)-4-phenyl-4,5-dihydroimidazolones | - |
| dc.subject.keyword | cytotoxicity | - |
| dc.subject.keyword | substituent's effect | - |
| dc.subject.local | 1-(1-Benzoylindoline-5-sulfonyl)-4-phenyl-4,5-dihydroimidazolones | - |
| dc.subject.local | Cytotoxicity | - |
| dc.subject.local | cytotoxicity | - |
| dc.subject.local | substituent's effect | - |
| dc.description.journalClass | Y | - |
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