DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sang Jick Kim | - |
dc.contributor.author | Young Woo Park | - |
dc.contributor.author | Hyo Jeong Hong | - |
dc.date.accessioned | 2017-04-19T09:03:17Z | - |
dc.date.available | 2017-04-19T09:03:17Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 1016-8478 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/7068 | - |
dc.description.abstract | Therapeutic antibodies represent one of the fastest growing areas of the pharmaceutical industry. There are currently 19 monoclonal antibodies in the market that have been approved by the FDA and over 150 in clinical developments. Driven by innovation and technological developments, therapeutic antibodies are the second largest biopharmaceutical product category after vaccines. Antibodies have been engineered by a variety of methods to suit a particular therapeutic use. This review describes the structural and functional characteristics of antibody and the antibody engineering for the generation and optimization of therapeutic antibodies. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | Antibody engineering for the development of therapeutic antibodies | - |
dc.title.alternative | Antibody engineering for the development of therapeutic antibodies | - |
dc.type | Article | - |
dc.citation.title | Molecules and Cells | - |
dc.citation.number | 1 | - |
dc.citation.endPage | 29 | - |
dc.citation.startPage | 17 | - |
dc.citation.volume | 20 | - |
dc.contributor.affiliatedAuthor | Sang Jick Kim | - |
dc.contributor.affiliatedAuthor | Young Woo Park | - |
dc.contributor.affiliatedAuthor | Hyo Jeong Hong | - |
dc.contributor.alternativeName | 김상직 | - |
dc.contributor.alternativeName | 박영우 | - |
dc.contributor.alternativeName | 홍효정 | - |
dc.identifier.bibliographicCitation | Molecules and Cells, vol. 20, no. 1, pp. 17-29 | - |
dc.subject.keyword | affinity Maturation | - |
dc.subject.keyword | antibody engineering | - |
dc.subject.keyword | antibody fragments | - |
dc.subject.keyword | effector functions | - |
dc.subject.keyword | human monoclonal antibodies | - |
dc.subject.keyword | humanized antibodies | - |
dc.subject.keyword | pharmacokinetics | - |
dc.subject.keyword | therapeutic antibodies | - |
dc.subject.local | affinity maturation | - |
dc.subject.local | affinity Maturation | - |
dc.subject.local | Affinity maturation | - |
dc.subject.local | antibody engineering | - |
dc.subject.local | Antibody engineering | - |
dc.subject.local | antibody fragments | - |
dc.subject.local | Antibody fragment | - |
dc.subject.local | effector functions | - |
dc.subject.local | Effector function | - |
dc.subject.local | Human monoclonal antibody | - |
dc.subject.local | human monoclonal antibodies | - |
dc.subject.local | human monoclonal antibody | - |
dc.subject.local | Humanized antibody | - |
dc.subject.local | humanized antibodies | - |
dc.subject.local | humanized antibody | - |
dc.subject.local | pharmacokinetics | - |
dc.subject.local | Pharmacokinetics | - |
dc.subject.local | therapeutic antibodies | - |
dc.description.journalClass | Y | - |
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