Antibody engineering for the development of therapeutic antibodies

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dc.contributor.authorSang Jick Kim-
dc.contributor.authorYoung Woo Park-
dc.contributor.authorHyo Jeong Hong-
dc.date.accessioned2017-04-19T09:03:17Z-
dc.date.available2017-04-19T09:03:17Z-
dc.date.issued2005-
dc.identifier.issn1016-8478-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/7068-
dc.description.abstractTherapeutic antibodies represent one of the fastest growing areas of the pharmaceutical industry. There are currently 19 monoclonal antibodies in the market that have been approved by the FDA and over 150 in clinical developments. Driven by innovation and technological developments, therapeutic antibodies are the second largest biopharmaceutical product category after vaccines. Antibodies have been engineered by a variety of methods to suit a particular therapeutic use. This review describes the structural and functional characteristics of antibody and the antibody engineering for the generation and optimization of therapeutic antibodies.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleAntibody engineering for the development of therapeutic antibodies-
dc.title.alternativeAntibody engineering for the development of therapeutic antibodies-
dc.typeArticle-
dc.citation.titleMolecules and Cells-
dc.citation.number1-
dc.citation.endPage29-
dc.citation.startPage17-
dc.citation.volume20-
dc.contributor.affiliatedAuthorSang Jick Kim-
dc.contributor.affiliatedAuthorYoung Woo Park-
dc.contributor.affiliatedAuthorHyo Jeong Hong-
dc.contributor.alternativeName김상직-
dc.contributor.alternativeName박영우-
dc.contributor.alternativeName홍효정-
dc.identifier.bibliographicCitationMolecules and Cells, vol. 20, no. 1, pp. 17-29-
dc.subject.keywordaffinity Maturation-
dc.subject.keywordantibody engineering-
dc.subject.keywordantibody fragments-
dc.subject.keywordeffector functions-
dc.subject.keywordhuman monoclonal antibodies-
dc.subject.keywordhumanized antibodies-
dc.subject.keywordpharmacokinetics-
dc.subject.keywordtherapeutic antibodies-
dc.subject.localaffinity maturation-
dc.subject.localaffinity Maturation-
dc.subject.localAffinity maturation-
dc.subject.localantibody engineering-
dc.subject.localAntibody engineering-
dc.subject.localantibody fragments-
dc.subject.localAntibody fragment-
dc.subject.localeffector functions-
dc.subject.localEffector function-
dc.subject.localHuman monoclonal antibody-
dc.subject.localhuman monoclonal antibodies-
dc.subject.localhuman monoclonal antibody-
dc.subject.localHumanized antibody-
dc.subject.localhumanized antibodies-
dc.subject.localhumanized antibody-
dc.subject.localpharmacokinetics-
dc.subject.localPharmacokinetics-
dc.subject.localtherapeutic antibodies-
dc.description.journalClassY-
Appears in Collections:
Synthetic Biology and Bioengineering Research Institute > Synthetic Biology Research Center > 1. Journal Articles
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