The effect of flavonol glycoside on the expressions of matrix metalloproteinase-1 in ultraviolet-irradiated cultured human skin fibroblasts

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dc.contributor.authorH I Moon-
dc.contributor.authorJoongku Lee-
dc.contributor.authorO P Zee-
dc.contributor.authorJ H Chung-
dc.date.accessioned2017-04-19T09:03:21Z-
dc.date.available2017-04-19T09:03:21Z-
dc.date.issued2005-
dc.identifier.issn0378-8741-
dc.identifier.uri10.1016/j.jep.2005.04.032ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/7090-
dc.description.abstractLong-term and repeated exposure of ultraviolet (UV) light, a harmful environmental stress, on the skin often induces chronic skin diseases, such as skin cancer as well as photo-aging (premature skin aging), and the mechanisms of these skin damages are closely associated with up-regulation of matrix metalloproteinases (MMPs) activities. Here, we investigated the effect of quercetin-3-O-β-d-(6″-feruloyl)-galactopyranoside isolated from the stems of Viola hondoensis (Violaceae) on the expression of MMPs in UV-irradiated human skin fibroblasts in vitro. Quercetin-3-O-β-d-(6″-feruloyl)- galactopyranoside markedly reduced UV-induced MMP-1 expression at the protein levels in a dose-dependent manner. Our report is the first description for the ability of quercetin-3-O-β-d-(6″-feruloyl)-galactopyranoside to regulate UV-induced MMP-1 expression.-
dc.publisherElsevier-
dc.titleThe effect of flavonol glycoside on the expressions of matrix metalloproteinase-1 in ultraviolet-irradiated cultured human skin fibroblasts-
dc.title.alternativeThe effect of flavonol glycoside on the expressions of matrix metalloproteinase-1 in ultraviolet-irradiated cultured human skin fibroblasts-
dc.typeArticle-
dc.citation.titleJournal of Ethnopharmacology-
dc.citation.number1-
dc.citation.endPage179-
dc.citation.startPage176-
dc.citation.volume101-
dc.contributor.affiliatedAuthorJoongku Lee-
dc.contributor.alternativeName문형인-
dc.contributor.alternativeName이중구-
dc.contributor.alternativeName지옥표-
dc.contributor.alternativeName정진호-
dc.identifier.bibliographicCitationJournal of Ethnopharmacology, vol. 101, no. 1, pp. 176-179-
dc.identifier.doi10.1016/j.jep.2005.04.032-
dc.subject.keywordMMP-1-
dc.subject.keywordquercetin-3-O-β-d-(6″-feruloyl)- galactopyranoside-
dc.subject.keywordultraviolet-
dc.subject.keywordviola hondoensis-
dc.subject.localMMP-1-
dc.subject.localquercetin-3-O-β-d-(6″-feruloyl)- galactopyranoside-
dc.subject.localultraviolet-
dc.subject.localUltraviolet-
dc.subject.localviola hondoensis-
dc.subject.localViola hondoensis-
dc.description.journalClassY-
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