Inhibitory activity of 6-O-angeloylprenolin from Centipeda minima on farnesyl protein transferase = 식물체로부터 FPTase 저해제 분리
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hyun Mi Oh | - |
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.contributor.author | N I Baek | - |
| dc.contributor.author | S H Kim | - |
| dc.contributor.author | J H Lee | - |
| dc.contributor.author | J S Eun | - |
| dc.contributor.author | J H Yang | - |
| dc.contributor.author | D K Kim | - |
| dc.date.accessioned | 2017-04-19T09:04:06Z | - |
| dc.date.available | 2017-04-19T09:04:06Z | - |
| dc.date.issued | 2006 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | 10.1007/BF02977470 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/7297 | - |
| dc.description.abstract | The methanolic extract of the aerial parts of Centipeda minima was found to show inhibitory activity on famesyl protein transferase (FPTase). Bioassay-guided fractionation of the methanolic extract resulted in the isolation of 6-O-angeloylprenolin, as an inhibitor on FPTase. This compound inhibited FPTase activity in a dose-dependent manner, and the IC50 value of 6-O-angeloylprenolin was 18.8 μM. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | Inhibitory activity of 6-O-angeloylprenolin from Centipeda minima on farnesyl protein transferase = 식물체로부터 FPTase 저해제 분리 | - |
| dc.title.alternative | Inhibitory activity of 6-O-angeloylprenolin from Centipeda minima on farnesyl protein transferase | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 1 | - |
| dc.citation.endPage | 66 | - |
| dc.citation.startPage | 64 | - |
| dc.citation.volume | 29 | - |
| dc.contributor.affiliatedAuthor | Hyun Mi Oh | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.alternativeName | 오현미 | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.contributor.alternativeName | 백남인 | - |
| dc.contributor.alternativeName | 김성훈 | - |
| dc.contributor.alternativeName | 이재혁 | - |
| dc.contributor.alternativeName | 은재순 | - |
| dc.contributor.alternativeName | 양재헌 | - |
| dc.contributor.alternativeName | 김대근 | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 29, no. 1, pp. 64-66 | - |
| dc.identifier.doi | 10.1007/BF02977470 | - |
| dc.subject.keyword | 6-O-Angeloylprenolin | - |
| dc.subject.keyword | Centipeda minima | - |
| dc.subject.keyword | FPTase | - |
| dc.subject.local | 6-O-Angeloylprenolin | - |
| dc.subject.local | Centipeda minima | - |
| dc.subject.local | FPTase | - |
| dc.description.journalClass | Y | - |
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