N-Benzylbenzamides: A new class of potent tyrosinase inhibitors
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | S J Cho | - |
| dc.contributor.author | J S Roh | - |
| dc.contributor.author | W S Sun | - |
| dc.contributor.author | S H Kim | - |
| dc.contributor.author | K D Park | - |
| dc.date.accessioned | 2017-04-19T09:06:22Z | - |
| dc.date.available | 2017-04-19T09:06:22Z | - |
| dc.date.issued | 2006 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | 10.1016/j.bmcl.2006.02.018 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/7750 | - |
| dc.description.abstract | A series of potent inhibitors of tyrosinase and their structure-activity relationships are described. N-Benzylbenzamide derivatives (1-21) with hydroxyl(s) were synthesized and tested for their tyrosinase inhibitory activity. With this series, compound 15 provided a potent tyrosinase inhibition: it effectively inhibited the oxidation of l-DOPA catalyzed by mushroom tyrosinase with an IC50 of 2.2 μM. | - |
| dc.publisher | Elsevier | - |
| dc.title | N-Benzylbenzamides: A new class of potent tyrosinase inhibitors | - |
| dc.title.alternative | N-Benzylbenzamides: A new class of potent tyrosinase inhibitors | - |
| dc.type | Article | - |
| dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
| dc.citation.number | 10 | - |
| dc.citation.endPage | 2684 | - |
| dc.citation.startPage | 2682 | - |
| dc.citation.volume | 16 | - |
| dc.contributor.affiliatedAuthor | K D Park | - |
| dc.contributor.alternativeName | 조성진 | - |
| dc.contributor.alternativeName | 노정섭 | - |
| dc.contributor.alternativeName | 선원석 | - |
| dc.contributor.alternativeName | 김성한 | - |
| dc.contributor.alternativeName | 박기덕 | - |
| dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 10, pp. 2682-2684 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2006.02.018 | - |
| dc.subject.keyword | 4-Substituted resorcinol | - |
| dc.subject.keyword | N-Benzylbenzamides | - |
| dc.subject.keyword | SAR | - |
| dc.subject.keyword | Tyrosinase inhibitor | - |
| dc.subject.local | 4-Substituted resorcinol | - |
| dc.subject.local | N-Benzylbenzamides | - |
| dc.subject.local | SAR | - |
| dc.subject.local | SAR (structure-activity relationship) | - |
| dc.subject.local | Tyrosinase inhibitor | - |
| dc.subject.local | tyrosinase inhibitor | - |
| dc.subject.local | Tyrosinase inhibitors | - |
| dc.description.journalClass | Y | - |
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