Hepatopotective effects of black rice on superoxide anion radicals in HepG2 cells

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Title
Hepatopotective effects of black rice on superoxide anion radicals in HepG2 cells
Author(s)
S Shim; Jin Woong Chung; J Lee; K Hwang; J Sone; B Hong; H Cho; W Jun
Bibliographic Citation
Food Science and Biotechnology, vol. 15, no. 6, pp. 993-996
Publication Year
2006
Abstract
Cyanidin 3-glucoside (C3G) isolated from black rice was investigated for hepatoprotective effects in HepG2 cells under oxidative stress. When an increase in the production of reactive oxygen species (ROS) was induced by gramoxone, cell viability was drastically decreased by 42%. However, in the presence of C3G, no hepatocytic damage was observed in HepG2 cells treated with gramoxone. C3G was found to manifest a stronger scavenging effect (91%) on superoxide anion radical (O₂-) than any of the other natural and synthetic antioxidants.
Keyword
black ricecyanidin 3-glucosideoxidative stresssuperoxide anion radicalHepG2 cell
ISSN
1226-7708
Publisher
South Korea
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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