Optimal culture conditions on the tyrosinase inhibitor production by actinomycetes F-97 = 방선균 F-97에 의한 Tyrosinase 저해제 생성 최적 배양 조건

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Title
Optimal culture conditions on the tyrosinase inhibitor production by actinomycetes F-97 = 방선균 F-97에 의한 Tyrosinase 저해제 생성 최적 배양 조건
Author(s)
B H Bang; Moon Soo Rhee; J O Kim; D H Yi
Bibliographic Citation
Korean Journal of Life Sciences, vol. 17, no. 6, pp. 798-804
Publication Year
2007
Abstract
A Actinomycetes F-97 producing tyrosinase inhibitor was isolated from soil samples. The optimum culture condition for tyrosinase inhibitor production was investigated and the results were as follows. The best carbon source for tyrosinase inhibitor production was shown as soluble starch, the optimum concentration was 3.0%. The best nitrogen source for tyrosinase inhibitor production was shown as peptone, the optimum concentration was 0.36%. As effect of metal ions on the production of tyrosinase inhibitor, K2HPO4 was shown the best and the optimum concentration was 0.1 mM. The optimum pH and temperature was shown 7.0 and 30℃, respectively. And the highest tyrosinase inhibitor production was observed at 70 hr cultivation under optimum conditions in jar fermentor scale.
Keyword
melanintyrosinasetyrosinase inhibitoractinomycetes
ISSN
I000-0052
Publisher
South Korea
DOI
http://dx.doi.org/10.5352/JLS.2007.17.6.798
Type
Article
Appears in Collections:
Jeonbuk Branch Institute > Biological Resource Center > 1. Journal Articles
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