Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Isolation of Sorangium cellulosum carrying epothilone gene clusters
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | H Hyun | - |
| dc.contributor.author | J Chung | - |
| dc.contributor.author | Jihoon Kim | - |
| dc.contributor.author | Jong Suk Lee | - |
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.contributor.author | Kwang Hee Son | - |
| dc.contributor.author | K Cho | - |
| dc.date.accessioned | 2017-04-19T09:11:39Z | - |
| dc.date.available | 2017-04-19T09:11:39Z | - |
| dc.date.issued | 2008 | - |
| dc.identifier.issn | 1017-7825 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8584 | - |
| dc.description.abstract | Epothilone and its analogs are a potent new class of anticancer compounds produced by myxobacteria. Thus, in an effort to identify new myxobacterial strains producing epothilone and its analogs, cellulose-degrading myxobacteria were isolated from Korean soils, and 13 strains carrying epothilone biosynthetic gene homologs were screened using a polymerase chain reaction. A migration assay revealed that Sorangium cellulosum KYC3013, 3016, 3017, and 3018 all produced microtubule-stabilizing compounds, and an LCMS/MS analysis showed that S. cellulosum KYC3013 synthesized epothilone A. | - |
| dc.publisher | Korea Soc-Assoc-Inst | - |
| dc.title | Isolation of Sorangium cellulosum carrying epothilone gene clusters | - |
| dc.title.alternative | Isolation of Sorangium cellulosum carrying epothilone gene clusters | - |
| dc.type | Article | - |
| dc.citation.title | Journal of Microbiology and Biotechnology | - |
| dc.citation.number | 8 | - |
| dc.citation.endPage | 1422 | - |
| dc.citation.startPage | 1416 | - |
| dc.citation.volume | 18 | - |
| dc.contributor.affiliatedAuthor | Jihoon Kim | - |
| dc.contributor.affiliatedAuthor | Jong Suk Lee | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.affiliatedAuthor | Kwang Hee Son | - |
| dc.contributor.alternativeName | 현혜숙 | - |
| dc.contributor.alternativeName | 정진우 | - |
| dc.contributor.alternativeName | 김지훈 | - |
| dc.contributor.alternativeName | 이종석 | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.contributor.alternativeName | 손광희 | - |
| dc.contributor.alternativeName | 조경연 | - |
| dc.identifier.bibliographicCitation | Journal of Microbiology and Biotechnology, vol. 18, no. 8, pp. 1416-1422 | - |
| dc.subject.keyword | epothilone | - |
| dc.subject.keyword | myxobacteria | - |
| dc.subject.keyword | sorangium cellulosum | - |
| dc.subject.local | epothilone | - |
| dc.subject.local | myxobacteria | - |
| dc.subject.local | sorangium cellulosum | - |
| dc.description.journalClass | Y | - |
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