DC Field | Value | Language |
---|---|---|
dc.contributor.author | In Ja Ryoo | - |
dc.contributor.author | B S Yun | - |
dc.contributor.author | I K Lee | - |
dc.contributor.author | Y H Kim | - |
dc.contributor.author | Ick Soo Lee | - |
dc.contributor.author | Jong Seog Ahn | - |
dc.contributor.author | K Bae | - |
dc.contributor.author | Ick Dong Yoo | - |
dc.date.accessioned | 2017-04-19T09:19:29Z | - |
dc.date.available | 2017-04-19T09:19:29Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | 10.4014/jmb.1004.04028 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/9687 | - |
dc.description.abstract | In an ongoing investigation of compounds from natural products that exhibit anti-aging properties, hydroxyhibiscone A (1), a new furanosesquiterpenoid, together with hibiscone D (2), was isolated from the root bark of Hibiscus syriacus. Utilizing UV, IR, NMR, and MS spectroscopic analyses, these chemical structures were revealed. Compounds 1 and 2 were found to posses significant anti-aging properties on the human neutrophil elastase (HNE) assay, exhibiting HNE inhibitory activities with IC50 values of 5.2 and 4.6 μM, respectively. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | Hydroxyhibiscone A, a novel human neutrophil elastase inhibitor from Hibiscus syriacus | - |
dc.title.alternative | Hydroxyhibiscone A, a novel human neutrophil elastase inhibitor from Hibiscus syriacus | - |
dc.type | Article | - |
dc.citation.title | Journal of Microbiology and Biotechnology | - |
dc.citation.number | 8 | - |
dc.citation.endPage | 1191 | - |
dc.citation.startPage | 1189 | - |
dc.citation.volume | 20 | - |
dc.contributor.affiliatedAuthor | In Ja Ryoo | - |
dc.contributor.affiliatedAuthor | Ick Soo Lee | - |
dc.contributor.affiliatedAuthor | Jong Seog Ahn | - |
dc.contributor.affiliatedAuthor | Ick Dong Yoo | - |
dc.contributor.alternativeName | 류인자 | - |
dc.contributor.alternativeName | 윤봉식 | - |
dc.contributor.alternativeName | 이인경 | - |
dc.contributor.alternativeName | 김영희 | - |
dc.contributor.alternativeName | 이익수 | - |
dc.contributor.alternativeName | 안종석 | - |
dc.contributor.alternativeName | 배기환 | - |
dc.contributor.alternativeName | 유익동 | - |
dc.identifier.bibliographicCitation | Journal of Microbiology and Biotechnology, vol. 20, no. 8, pp. 1189-1191 | - |
dc.identifier.doi | 10.4014/jmb.1004.04028 | - |
dc.subject.keyword | Hibiscus syriacus | - |
dc.subject.keyword | Human neutrophil elastase | - |
dc.subject.keyword | Hydroxyhibiscone A | - |
dc.subject.local | Hibiscus syriacus | - |
dc.subject.local | Hibiscus syriacus L. | - |
dc.subject.local | Human neutrophil elastase | - |
dc.subject.local | human neutrophil elastase | - |
dc.subject.local | Hydroxyhibiscone A | - |
dc.description.journalClass | Y | - |
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