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Results 1-12 of 12 (Search time: 0.003 seconds).

No. Year Title Type
12 2023


Discovery of pan-IAP degraders via a CRBN recruiting mechanismEuropean Journal of Medicinal Chemistry, vol. 245, no. 2, pp. 114910-114910Seulki Park; D Kim; W Lee; Jin Hwa Cho; Sungyoung Kim; Ga Seul Lee; Jeong Hee MoonJung Ae Kim; J D Ha; Jeong Hoon Kim, et al.
11 2023

2023Research Project

단백질 분해 기반 신약개발 플랫폼 기술 개발 = Development of drug discovery platform based on targeted protein degradation연구책임자 : 김정훈 / 사업기간 : 2023.01.01 ~ 2023.12.31
Research Project
10 2022


Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse modelBioorganic Chemistry, vol. 127, pp. 105923-105923A D Takwale; E Y Kim; Y Jang; D H Lee; S Kim; Y Choi; J H Kim; D Y Lee; Y Kim; S M Lee, et al.
9 2022


Artificial intelligence-based identification of octenidine as a Bcl-xL inhibitorBiochemical and Biophysical Research Communications, vol. 588, pp. 97-103A R N Bui; H Son; Seulki Park; Sohee Oh; Jin Sik KimJin Hwa Cho; Hye-Jin Hwang; Jeong Hoon Kim; G S Yi; Seung-Wook Chi
8 2022

2022Research Project

단백질 분해 기반 신약개발 플랫폼 기술 개발 = Development of drug discovery platform based on targeted protein degradation연구책임자 : 김정훈 / 사업기간 : 2022.01.01 ~ 2022.12.31
Research Project
7 2021


Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathwaysCell Death and Differentiation, vol. 28, no. 3, pp. 900-914Jin Hwa Cho; Kidae Kim; Sung Ah Kim; Seongryul Park; Bi-Oh Park; Jong Hwan KimSeon-Young Kim; M J Kwon; M H Han; S B Lee, et al.
6 2021


Phosphorylation of REPS1 at Ser709 by RSK attenuates the recycling of Transferrin receptorBMB Reports, vol. 54, no. 5, pp. 272-277Seong Heon Kim; Jin Hwa Cho; Bi-Oh Park; Byoung Chul ParkJeong Hoon KimSung Goo Park; Sunhong Kim
5 2020


Aryl sulfonamides induce degradation of aryl hydrocarbon receptor nuclear translocator through crl4dcaf15 e3 ligaseMolecules and Cells, vol. 43, no. 11, pp. 935-944Sung Ah Kim; Seung-Hyun Jo; Jin Hwa Cho; Min Yeong Yu; Ho Chul ShinJung Ae KimSung Goo ParkByoung Chul Park; Sunhong Kim; Jeong Hoon Kim
4 2018


Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XLJournal of Biological Chemistry, vol. 293, no. 51, pp. 19546-19558Mi-Kyung Yoon; B Y Kim; J Y Lee; Ji-Hyang Ha; Sung Ah Kim; Dong-Hwa Lee; Min-Sung Lee; Mi-Kyung Lee; Jin Sun Choi; Jin Hwa Cho, et al.
3 2017


The p90 ribosomal S6 kinase-UBR5 pathway controls Toll-like receptor signaling via miRNA-induced translational inhibition of tumor necrosis factor receptor-associated factor 3 = TRAF3의 miRNA 유도 번역저해를 통한 p90RSK-UBR5 신호전달계의 Toll-like 수용체 신호 조절Journal of Biological Chemistry, vol. 292, no. 28, pp. 11804-11814Jin Hwa Cho; Sung Ah Kim; Y S Seo; Sung Goo ParkByoung Chul ParkJeong-Hoon Kim; Sunhong Kim
2 2014


Expression of the pro-domain-deleted active form of caspase-6 in Escherichia coliJournal of Microbiology and Biotechnology, vol. 24, no. 5, pp. 719-723Phil Young Lee; Jin Hwa ChoSeung-Wook ChiKwang-Hee Bae; S Cho; Byoung Chul ParkJeong Hoon KimSung Goo Park
1 2013


Identification of the novel substrates for caspase-6 in apoptosis using proteomic approachesBMB Reports, vol. 46, no. 12, pp. 588-593Jin Hwa Cho; Phil Young Lee; W C Son; Seung-Wook ChiByoung Chul ParkJeong Hoon KimSung Goo Park