Disease Target Structure Research Center (질환표적구조연구센터)
Results 1-20 of 104 (Search time: 0.006 seconds).
No. | Year | Title | Type |
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104 | 2024 | 2024Patent 수용체형 단백질 티로신 탈인산화효소의 이량체화 억제제의 스크리닝 방법KR10-2021-0091787 (2021.07.13) / 10-2628529-0000 (2024.01.18)신호철; 정다은; 김승준; 구본수; 이혜선 |
Patent |
103 | 2024 | 2024Article Crystal structure of Bak bound to the BH3 domain of Bnip5, a non-canonical BH3 domain-containing proteinProteins-Structure Function and Bioinformatics, vol. 92, no. 1, pp. 44-51Dahwan Lim; Da Eun Jeong; Ho Chul Shin; J S Choi; Jinho Seo; Seung Jun Kim; Bonsu Ku |
Article |
102 | 2024 | 2024Article Macrocephaly and digital anomalies expand the phenotypic spectrum of PGAP2 variants in hyperphosphatasia with impaired intellectual development syndrome 3 (HPMRS3)Human Mutation, vol. 2024, pp. 5518289-5518289S Susgun; A Ben-Mahmoud; F Ruschendorf; Bonsu Ku; S I Hussain; S Schulz; O Puk; S Biskup; J D J Labonne; D W Don, et al. |
Article |
101 | 2023 | 2023Report 인유두종 바이러스 E6, E7 암 유발 단백질 복합체 삼차구조 규명을 통한 발병 기작 이해 = Molecular analysis of the HPV E6, E7 viral oncoprotein complex structure연구책임자 : 구본수 / 주관부처 : 과학기술정보통신부구본수 |
Report |
100 | 2023 | Report | |
99 | 2023 | 2023Article Influenza viral matrix 1 protein aggravates viral pathogenicity by inducing TLR4-mediated reactive oxygen species production and apoptotic cell deathCell Death & Disease, vol. 14, no. 3, pp. 228-228Chang Ung Kim; Dahwan Lim; Y S Kim; Bonsu Ku; Doo-Jin Kim |
Article |
98 | 2023 | 2023Research Project 신약 발굴을 위한 나노포어 플랫폼 기술 개발 = Development of nanopore platform technology for drug discovery연구책임자 : 지승욱 / 사업기간 : 2023.01.01 ~ 2023.12.31 |
Research Project |
97 | 2023 | 2023Research Project 가속기 연구소의 물질조각 탐색 시스템을 활용한 신약후보물질 발굴 = Identification of drug candidates using the fragment screening system of Pohang Accelerator Laboratory연구책임자 : 구본수 / 사업기간 : 2023.01.01 ~ 2023.12.31 |
Research Project |
96 | 2023 | 2023Article A fluorescent probe to simultaneously detect both O-GlcNAcase and phosphataseFrontiers in Chemistry, vol. 11, pp. 1133018-1133018J Boo; J Lee; Y H Kim; C H Lee; Bonsu Ku; I Shin |
Article |
95 | 2023 | 2023Article Structural analysis of the interaction between Bcl-xL and the noncanonical BH3 domain of non-Bcl-2 family proteinsCurrent Protein & Peptide Science, vol. 24, no. 4, pp. 296-306Bonsu Ku |
Article |
94 | 2023 | 2023Article Crystal structures of Plk1 polo-box domain bound to the human papillomavirus minor capsid protein L2-derived peptideJournal of Microbiology, vol. 61, pp. 755-764Sujin Jung; Hye Seon Lee; Ho Chul Shin; J S Choi; Seung Jun Kim; Bonsu Ku |
Article |
93 | 2023 | 2023Article Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1PLoS Biology, vol. 21, no. 6, pp. e3002156-e3002156Dahwan Lim; So Hui Choe; Sein Jin; S Lee; Y Kim; Ho Chul Shin; J S Choi; Doo-Byoung Oh; Seung Jun Kim; Jinho Seo, et al. |
Article |
92 | 2023 | 2023Article Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cellsCommunications Biology, vol. 6, pp. 712-712J I Ahn; L Zhang; H Ravishankar; L Fan; K Kirsch; Y Zeng; L Meng; J E Park; Hyeyoung Yoon; R Ghirlando, et al. |
Article |
91 | 2023 | 2023Article Identification of two novel autism genes, TRPC4 and SCFD2, in Qatar simplex families through exome sequencingFrontiers in Psychiatry, vol. 14, pp. 1251884-1251884V Gupta; A Ben-Mahmoud; Bonsu Ku; D Velayutham; Z Jan; A Y Aden; A Kubbar; F Alshaban; L W Stanton; P V Jithesh, et al. |
Article |
90 | 2023 | 2023Article Insights into the recognition mechanism in the UBR box of UBR4 for its specific substratesCommunications Biology, vol. 6, pp. 1214-1214Da Eun Jeong; Hye Seon Lee; Bonsu Ku; C H Kim; Seung Jun Kim; Ho Chul Shin |
Article |
89 | 2022 | 2022Article Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoproteinJournal of Microbiology, vol. 60, no. 4, pp. 395-401Hye Seon Lee; Hye-Yeoung Yun; Eun-Woo Lee; Ho-Chul Shin; Seung Jun Kim; Bonsu Ku |
Article |
88 | 2022 | 2022Research Project 신약 발굴을 위한 나노포어 플랫폼 기술 개발 = Development of nanopore platform technology for drug discovery연구책임자 : 지승욱 / 사업기간 : 2022.01.01 ~ 2022.12.31 |
Research Project |
87 | 2022 | 2022Research Project 가속기 연구소의 물질조각 탐색 시스템을 활용한 신약후보물질 발굴 = Identification of drug candidates using the fragment screening system of Pohang Accelerator Laboratory연구책임자 : 구본수 / 사업기간 : 2022.01.01 ~ 2022.12.31 |
Research Project |
86 | 2022 | 2022Article Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1Biochemical and Biophysical Research Communications, vol. 625, pp. 174-180Dahwan Lim; Sein Jin; Ho-Chul Shin; W Kim; J S Choi; Doo-Byoung Oh; Seung Jun Kim; Jinho Seo; Bonsu Ku |
Article |
85 | 2022 | 2022Research Project 인유두종 바이러스 E6, E7 암 유발 단백질 복합체 삼차구조 규명을 통한 발병 기작 이해 = Molecular analysis of the HPV E6, E7 viral oncoprotein complex structure연구책임자 : 구본수 / 사업기간 : 2022.03.01 ~ 2023.02.28 |
Research Project |