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Results 1-13 of 13 (Search time: 0.004 seconds).

No. Year Title Type
13 2021

2021Article

Aristolactam BIII, a naturally derived DYRK1A inhibitor, rescues Down syndrome-related phenotypes = 식물 천연물 유래 DYRK1A 억제물질 aristolactam BIII의 다운증후군 개선효능Phytomedicine, vol. 92, pp. 153695-153695Miri Choi; Ae-Kyeong Kim; Youngwook Ham; J Y Lee; Daeyong Kim; Ansook Yang; Min Ju Jo; E Yoon; J N Heo; S B Han, et al.
Article
12 2021

2021Article

Lipophorin receptor 1 (LpR1) in Drosophila muscle influences life span by regulating mitochondrial agingBiochemical and Biophysical Research Communications, vol. 568, pp. 95-102Ae-Kyeong Kim; Dae Woo Kwon; Eunbyul Yeom; Kwang-Pyo LeeKi-Sun KwonKweon YuKyu-Sun Lee
Article
11 2020

2020Article

A novel de novo heterozygous DYRK1A mutation causes complete loss of DYRK1A function and developmental delay = DYRK1A 신규 돌연변이 기능연구Scientific Reports, vol. 10, pp. 9849-9849Kyu-Sun Lee; Miri Choi; Dae Woo Kwon; D Kim; J M Choi; Ae-Kyeong Kim; Yeongwook Ham; S B Han; Sungchan Cho; C K Cheon
Article
10 2020

2020Article

Loss of HSPA9 induces peroxisomal degradation by increasing pexophagyAutophagy, vol. 16, no. 11, pp. 1989-2003D S Jo; S J Park; Ae-Kyeong Kim; N Y Park; J B Kim; J E Bae; H J Park; J H Shin; J W Chang; P K Kim, et al.
Article
9 2018

2018Article

Altered ER-mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease modelsProceedings of National Academy of Sciences of United States of America, vol. 115, no. 38, pp. e8844-e8853Kyu-Sun Lee; S Huh; Lee Seongsoo; Z Wu; Ae-Kyeong Kim; H Y Kang; B Lu
Article
8 2017

2017Patent

CX-4945를 유효성분으로 함유하는 퇴행성 뇌질환 예방 및 치료용약학적조성물KR10-2015-0071667 (2015.05.22) / 10-1705226 (2017.02.03)유권이규선이정수조성찬김애경; 최미리; 최광만; 이민성; 김형기; 강현주, et al.
Patent
7 2016

2016Article

A chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibition = CX-4945의 DYRK1A 억제를 통한 다운증후군 결함 개선Disease Models & Mechanisms, vol. 9, no. 7, pp. 839-848Hyeongki Kim; Kyu-Sun LeeAe Kyung Kim; Miri Choi; Kwangman Choi; Mingu Kang; Seung-Wook Chi; Min-Sung Lee; Jeong Soo Lee; S Y Lee, et al.
Article
6 2015

2015Article

Photoexcited porphyrins as a strong suppressor of β-amyloid aggregation and synaptic toxicityAngewandte Chemie-International Edition, vol. 54, no. 39, pp. 11472-11476B I Lee; Seongsoo Lee; Yoon Seok Suh; J S Lee; Ae Kyung Kim; O Y Kwon; Kweon Yu; C B Park
Article
5 2014

2014Article

RNA-guided genome editing in Drosophila with the purified Cas9 proteinG3-Genes Genomes Genetics, vol. 4, no. 7, pp. 1291-1295Jeong Soo Lee; Su-Jin Kwak; J Kim; Ae Kyung Kim; Hae Min Noh; J S Kim; Kweon Yu
Article
4 2012

2012Article

Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammalsPLoS Genetics, vol. 8, no. 8, pp. 1002857-1002857Seung Hyun Hong; Kyu-Sun Lee; Su-Jin Kwak; Ae-Kyeong Kim; H Bai; M S Jung; O Y Kwon; W J Song; M Tatar; Kweon Yu
Article
3 2010

2010Article

The Drosophila homolog of methionine sulfoxide reductase A extends lifespan and increases nuclear localization of FOXOFEBS Letters, vol. 584, no. 16, pp. 3609-3614H CHung; Ae Kyeong Kim; S A Jung; S W Kim; Kweon Yu; J H Lee
Article
2 2009

2009Article

Processed short neuropeptide F peptides regulate growth through the ERK-insulin pathway in Drosophila melanogasterFEBS Letters, vol. 583, no. 15, pp. 2573-2577Kyu-Sun Lee; Seung Hyn Hong; Ae Kyung Kim; Seong Kyu Joo; O Y Kwon; Kweon Yu
Article
1 2008

2008Article

Drosophila short neuropeptide F signalling regulates growth by ERK-mediated insulin signallingNature Cell Biology, vol. 10, no. 4, pp. 468-475Kyu-Sun Lee; O Y Kwon; J H Lee; K Kwon; K J Min; S A Jung; Ae-Kyeong Kim; K H You; M Tatar; Kweon Yu
Article
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