Immunotherapy Research Center (면역치료제연구센터)820

연구분야

  • HSC 기반 유전자 NK세포치료제 개발 (PL1,2)
    • 융복합 NK세포치료 임상연구
    • CAR-NK 세포 치료제 개발
    • 단일세포 영상 기반 면역세포 효능 검증
    • 주입형 나노하이드로겔 복합체 기반 면역세포 3차원 배양기술 개발
  • 항암제 활용 맞춤형 혼합 NK세포치료제 개발 (PL3)
    • 암세포에 있어서 NK 세포의 공격에 대한 감수성을 높이는 항암제 개발
    • 줄기세포 유래 NK 세포 항암기능향상 항암제 개발
    • 간암 맞춤형 전임상을 통한 NK 세포 치료제와의 혼합치료 최적화 기술 개발
  • 생체 이미징을 이용한 전임상 동물모델에서의 면역세포치료 효능 검증
    • 이식된 세포에 대한 동물모델에서의 실시간 생체영상 추적으로 NK 세포치료 유효성 검증
    • 생체영상 치료효과 모니터링을 통한 NK, NK-항암제, NK-항체 치료에 대한 치료 유효성 검증
더보기

Showing results 1 to 20 of 576

No. Year Title Type
1 2011

2011Article

1,25-Dihydroxyvitamin D3 enhances NK susceptibility of human melanoma cells via Hsp60-mediated FAS expressionEuropean Journal of Immunology, vol. 41, no. 10, pp. 2937-2946J H Lee; S Park; S Cheon; J H Lee; S Kim; D Y Hur; T S Kim; Suk Ran Yoon; Y Yang; S I Bang, et al.
Article
2 2015

2015Article

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) modulates Th2 immunity through attenuation of IL-4 expressionImmune Network, vol. 15, no. 2, pp. 100-109S Y Yoon; Ho Bum Kang; Young Eun Go; Su Hyun Shin; Young-Jun Kim; K Y Sohn; Y H Han; S Chong; Jae Wha Kim
Article
3 2019

2019Article

1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) attenuates gemcitabine-induced neutrophil extravasationCell and Bioscience, vol. 9, pp. 4-4Jinseon Jeong; Y J Kim; D Y Lee; B G Moon; K Y Sohn; S Y Yoon; Jae Wha Kim
Article
4 2020

2020Article

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) mitigates monosodium urate (MSU)-induced acute gouty inflammation in BALB/c miceFrontiers in Immunology, vol. 11, pp. 710-710Su Hyun Shin; J Jeong; J H Kim; K Y Sohn; S Y Yoon; Jae Wha Kim
Article
5 2019

2019Article

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) rapidly resolves LPS-induced acute lung injury through the effective control of neutrophil recruitmentFrontiers in Immunology, vol. 10, pp. 2177-2177H R Lee; Su Hyun Shin; J H Kim; K Y Sohn; S Y Yoon; Jae Wha Kim
Article
6 2018

2018Article

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) reduces hepatic injury in concanavalin A-treated miceJournal of Cellular Biochemistry, vol. 119, no. 2, pp. 1392-1405Young Eun Ko; S Y Yoon; S Y Ly; J H Kim; K Y Sohn; Jae Wha Kim
Article
7 2017

2017Article

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates arthritic joints through reducing neutrophil infiltration mediated by IL-6/STAT3 and MIP-2 activationOncotarget, vol. 8, no. 57, pp. 96636-96648Young-Jun Kim; Jae Min Shin; Su-Hyun Shin; J H Kim; K Y Sohn; H J Kim; J K Kang; S Y Yoon; Jae Wha Kim
Article
8 2020

2020Article

1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates chemoradiation-induced oral mucositisOral Diseases, vol. 26, no. 1, pp. 111-121Solji Choi; Su Hyun Shin; H R Lee; K Y Sohn; S Y Yoon; Jae Wha Kim
Article
9 2020

2020Article

1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates EGF-induced MMP-9 expression by promoting receptor desensitization in MDA-MB-231 cellsOncology Reports, vol. 44, pp. 241-251Kwang Hoon Yang; Guen Tae Kim; Solji Choi; S Y Yoon; Jae Wha Kim
Article
10 2019

2019Article

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol attenuates streptozotocin-induced pancreatic beta cell damage by promoting glucose transporter 2 endocytosisMolecular and Cellular Biology, vol. 39, no. 21, pp. e00157-e00157Jimin Kim; J H Kim; K Y Sohn; S Y Yoon; Jae Wha Kim
Article
11 2024

2024Article

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol treatment inhibits abnormal tumor growth by regulating neutrophil infiltration in a non-small cell lung carcinoma mouse modelBiomedicine & Pharmacotherapy, vol. 178, pp. 117269-117269G Kim; E Y Kim; H Lee; S H Shin; S H Lee; K Y Sohn; Jae Wha Kim; J S Lee
Article
12 2015

2015Article

1-pamitoyl-2-linoleoyl-3-acetyl-rac-glycerol may reduce incidence of gemcitabine-induced neutropenia: A pilot case-controlled studyWorld Journal of Oncology, vol. 6, no. 4, pp. 410-415D Oh; M H Kim; T J Song; C J Cho; K Nam; M K Cho; J H Chun; K Jung; K P Kim; Jae Wha Kim
Article
13 2023

2023Article

6-Shogaol overcomes Gefitinib resistance via ER stress in ovarian cancer cellsInternational Journal of Molecular Sciences, vol. 24, no. 3, pp. 2639-2639T W Kim; Hee Gu Lee
Article
14 2012

2012Article

A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled studyBMC Pediatrics, vol. 12, no. 1, pp. 111-111J H Park; M Miyashita; Y C Kwon; H T Park; E H Kim; J K Park; K B Park; Suk Ran Yoon; J W Chung; Y Nakamura, et al.
Article
15 1993

1993Article

A case of left atrial Myxoma with increased Interleukin-6 = 다량의 Interleukin-6를 분비하는 심장점액종 1 예Korean Journal of Internal Medicine, vol. 45, no. 4, pp. 533-537Chan Soo Moon; Jae Kyung Choi; Wook Sung Chung; Kwang Mu Yoon; Ho Jung Yoon; Joon Chul Park; Jai Hyung Kim; Koy Bo Choi; Soon Jo Hong; Hyung Sik Kang, et al.
Article
16 2005

2005Article

A comparison of lyophilized amniotic membrane with cryopreserved amniotic membrane for the reconstruction of rabbit corneal epitheliumBiotechnology and Bioprocess Engineering, vol. 10, no. 3, pp. 262-269J I Ahn; I K Jang; D H Lee; Y K Seo; H H Yoon; Y H Shin; J C Kim; K Y Song; Hee Gu Lee; E K Yang, et al.
Article
17 2022

2022Article

A double-edged sword: the two faces of PARylationInternational Journal of Molecular Sciences, vol. 23, no. 17, pp. 9826-9826M Kang; S Park; S H Park; Hee Gu Lee; J H Park
Article
18 2023

2023Article

A modifiable universal cotinine-chimeric antigen system of NK cells with multiple targetsFrontiers in Immunology, vol. 13, pp. 1089369-1089369Hee Young Kang; Soo Yun Lee; H M Kim; Su Ui Lee; H Lee; M Y Cho; Se-Chan Oh; Seok-Min Kim; H S Park; E H Han, et al.
Article
19 2015

2015Article

A novel human model of the neurodegenerative disease GM1 gangliosidosis using induced pluripotent stem cells demonstrates inflammasome activationJournal of Pathology, vol. 237, no. 1, pp. 98-110Mi Young Son; Jae Eun Kwak; Binna SeolDa Yong Lee; Hyejin Jeon; Yee Sook Cho
Article
20 2012

2012Article

A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cellsAngewandte Chemie-International Edition, vol. 51, no. 50, pp. 12509-12513Jung Woon Lee; Y Xia; Mi Young Son; G Jin; Binna Seol; Min-Jeong Kim; Myung Jin Son; M Do; M Lee; D Kim, et al.
Article
1 2 3 4 5 6 7 8 9 10 11 29