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Open Access@KRIBBOchang Branch Institute Natural Product Research Center

Natural Product Research Center (천연물연구센터)902

연구분야

국내/해외 식물자원의 식물추출물 라이브러리 구축
만성염증질환(천식/COPD, atopy 등) 치료용 천연물소재 개발
대사성질환(비만, 당뇨) 치료용 천연물소재 개발
기능성 유전체학 및 단백체학에 근거한 천식/COPD 생체지표 개발
천연물대사체를 이용한 약용자원의 원산지판별 및 표준화

Showing results 1 to 20 of 588

No.	Year	Title	Type
1	2005	2005Article 1,12-Substituted tetracyclines as antioxidant agentsBioorganic & Medicinal Chemistry, vol. 13, no. 15, pp. 4627-4637J Lertvorachon; Jong Pyung Kim; D V Soldatov; J Boyd; G Roman; S J Cho; T Popek; Y S Jung; P C K Lau; Y Konishi	Article
2	2023	2023Article 1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surfaceOcular Surface, vol. 29, pp. 469-479C H Yoon; Hyun-Jae Jang; J S Ryu; J H Ko; Kyung Seop Ahn; Sei-Ryang Oh; J H Oh; J H Chung; J Y Oh	Article
3	2018	2018Article 3,4,5-Trihydroxycinnamic acid attenuates lipopolysaccharide (LPS)-induced acute lung injury via downregulating inflammatory molecules and upregulating HO-1/AMPK activationInternational Immunopharmacology, vol. 64, pp. 123-130Jae Won Lee; W Chun; Ok-Kyoung Kwon; Hyun Ah Park; Yourim Lim; Jae Hyeon Lee; Doo-Young Kim; Jung Hee Kim; Hyeong Kyu Lee; Hyung Won Ryu, et al.	Article
4	2020	2020Article 3,4,5-Trihydroxycinnamic acid exerts a protective effect on pulmonary inflammation in an experimental animal model of COPD = COPD 동물모델에서의 THCA의 폐염증 억제효과International Immunopharmacology, vol. 85, pp. 106656-106656Jae-Hong Min; Min-Gu Kim; Sung-Man Kim; Ji Won Park; W Chun; H J Lee; Sei-Ryang Oh; Kyung Seop Ahn; Jae Won Lee	Article
5	2020	2020Article 3,4,5-Trihydroxycinnamic acid exerts anti-asthmatic effects in vitro and in vivoInternational Immunopharmacology, vol. 88, pp. 107002-107002Ji Won Park; Seong-Man Kim; Jae-Hong Min; Min-Gu Kim; Ok-Kyoung Kwon; Daseul Hwang; Jae-Hoon Oh; M W Park; W Chun; H J Lee, et al.	Article
6	2021	2021Article 3,4,5-Trihydroxycinnamic acid exerts anti-inflammatory effects on TNF-α/IFN-γ-stimulated HaCaT cellsMolecular Medicine Reports, vol. 24, no. 1, pp. 509-509Ji Won Park; Jae-Hoon Oh; Daseul Hwang; Seong Man Kim; Jae-Hong Min; Ji-Yun Seo; W Chun; H J Lee; Sei-Ryang Oh; Jae-Won Lee, et al.	Article
7	2017	2017Article 3-Methoxy-catalposide inhibits inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophagesCytokine, vol. 91, pp. 57-64Hyung Won Ryu; Su Ui Lee; SeogHyun Lee; H H Song; Tae Hyun Son; Yeah Un Kim; Heung Joo Yuk; H Ro; C K Lee; S T Hong, et al.	Article
8	2015	2015Article 6-O-Veratroyl catalpol suppresses pro-inflammatory cytokines via regulation of extracellular signal-regulated kinase and nuclear factor-κB in human monocytic cellsBiochimie, vol. 119, pp. 52-59M Q Le; M S Kim; Y S Song; Hyung Won Ryu; Sei-Ryang Oh; D Y Yoon	Article
9	2005	2005Article 7-Ketocholesterol predisposes human aorta smooth muscle cells to Fas-mediated deathJournal of Molecular and Cellular Cardiology, vol. 39, no. 5, pp. 823-832Mun Chual Rho; Young Kook Kim; Jong Sun Chang; Hyun Sun Lee; Jin Ah Baek; Mi Yeon Chung; H C Lee; H W Lee; B Y Rhim; M A Reidy, et al.	Article
10	2018	2018Article 7-Methoxy-luteolin-8-C-β-6-deoxy-xylo-pyranos-3-uloside exactly (mLU8C-PU) isolated from Arthraxon hispidus inhibits migratory and invasive responses mediated via downregulation of MMP-9 and IL-8 expression in MCF-7 breast cancer cellsEnvironmental Toxicology, vol. 33, no. 11, pp. 1143-1152S J Kim; T H Pham; Y Bak; Hyung Won Ryu; Sei-Ryang Oh; D Y Yoon	Article
11	2021	2021Article 8-Epi-xanthatin induces the apoptosis of DU145 prostate carcinoma cells through signal transducer and activator of transcription 3 inhibition and reactive oxygen species generationPhytotherapy Research, vol. 35, pp. 1508-1520Yujin Lee; Jiyeon Choi; Yae Jin Yoon; Yugyeong Sim; Hyung Won Ryu; Sei-Ryang Oh; Doo-Young Kim; Jihyun Hwang; Seung-Wook Chi; Dong Cho Han, et al.	Article
12	2021	2021Article A combination of Olea europaea leaf extract and Spirodela polyrhiza extract alleviates atopic dermatitis by modulating immune balance and skin barrier function in a 1-chloro-2,4-dinitrobenzene-induced murine modelPhytomedicine, vol. 82, pp. 153407-153407Y S Lee; Hyung Won Ryu; W K Yang; Mi Hyeon Park; Y C Park; Doo-Young Kim; H J Kwon; S Y Kim; Sei-Ryang Oh; S H Kim	Article
13	1996	1996Article A herbicidal nucleoside compound isolated from Streptomyces tubercidicus ME-9189 = Streptomyces tubercidicus ME-9189 균주가 생산하는 nucleoside계 제초 활성 물질Korean Journal of (Applied) Microbiology & Biotechnology, vol. 24, no. 1, pp. 82-86Won Gon Kim; Jong Pyung Kim; Chang Jin Kim; Ick Dong Yoo	Article
14	2012	2012Article A leaf methanolic extract of Wercklea insignis attenuates the lipopolysaccharide-induced inflammatory response by blocking the NF-κB signaling pathway in RAW 264.7 macrophages = 워크리아의 항염증 활성Inflammation, vol. 35, no. 1, pp. 321-331Ji Won Park; Ok-Kyoung Kwon; Ha Young Jang; Hyouk Joung; Sei Ryang Oh; Hyeong Kyu Lee; S B Han; Kyung Seop Ahn	Article
15	2016	2016Article A metabolomics approach to identify factors influencing their activity relative to oleanolic acid contents in Korean mistletoe typesJournal of Functional Foods, vol. 22, pp. 64-72H H Song; Hyung Won Ryu; Hui Seong Kim; C S Kim; H J Hyun; Hyeong Kyu Lee; Sei-Ryang Oh	Article
16	2024	2024Article A metabolomics approach to identify factors influencing their α-glucosidase and hDPP-IV activity relative to chemical marker in adzuki bean (Vigna angularis (Willd.) Ohwi & H. Ohashi) cultivars = 팥(Vigna angularis (Willd.) Ohwi & H. Ohashi) 품종의 화학적 마커와 비교하여 항당뇨병 활성에 영향을 미치는 요인을 식별하기 위한 대사체학 접근법Journal of Applied Biological Chemistry, vol. 67, no. 1, pp. 105-112Seon Min Oh; Jongmin Ahn; S Jung; Ji-Yoon Park; Doo-Young Kim; Jung Hee Kim; S B Song; Y K Ju; J H Chu; Mun-Ock Kim, et al.	Article
17	2023	2023Article A modifiable universal cotinine-chimeric antigen system of NK cells with multiple targetsFrontiers in Immunology, vol. 13, pp. 1089369-1089369Hee Young Kang; Soo Yun Lee; H M Kim; Su Ui Lee; H Lee; M Y Cho; Se-Chan Oh; Seok-Min Kim; H S Park; E H Han, et al.	Article
18	1996	1996Article A new alkyl alcohol glycoside from Chrysanthemi Flos = 감국(Chrysanthemi Flos)의 새로운 알킬알콜배당체 성분에 관한 연구Korean Journal of Pharmacognosy, vol. 27, no. 1, pp. 15-19Keun Young Jung; Sei Ryang Oh; Chun Suk Kim; Jung Hee Kim; Hyeong Kyu Lee	Article
19	1997	1997Article A new cytotoxic phenylthiazoline, 4-methylaeruginoic acid, from Streptomyces sp. KCTC 9303Journal of Antibiotics, vol. 50, no. 3, pp. 256-258In Ja Ryoo; Kyung Sik Song; Jong Pyung Kim; Won Gon Kim; H Koshino; Ick Dong Yoo	Article
20	2014	2014Article A new dammarane-type triterpene with PTP1B inhibitory activity from Gynostemma pentaphyllumBulletin of Korean Chemical Society, vol. 35, no. 10, pp. 3122-3124N Li; Z D Tuo; S S Xing; S Z Qi; Hyun Sun Lee; L Cui	Article

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