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Results 1-20 of 44 (Search time: 0.005 seconds).

No. Year Title Type
44 2022

2022Article

In vivo toxicity and pharmacokinetics of polytetrafluoroethylene microplastics in ICR micePolymers, vol. 14, no. 11, pp. 2220-2220S Lee; K K Kang; S E Sung; J H Choi; M Sung; K Y Seong; J Lee; S Kang; S Y Yang; S Lee, et al.
Article
43 2022

2022Article

Regulation of drug transporters by microRNA and implications in disease treatmentJournal of Pharmaceutical Investigation, vol. 52, pp. 23-47Y J Chae; J E Chang; M K Lee; J Lim; K H Shin; Kyeong-Ryoon Lee
Article
42 2022

2022Article

Integration of a physiologically based pharmacokinetic and pharmacodynamic model for tegoprazan and its metabolite: application for predicting food effect and intragastric pH alterationsPharmaceutics, vol. 14, no. 6, pp. 1298-1298H C Jeong; M G Kim; Z Wei; Kyeong-Ryoon Lee; J Lee; I S Song; K H Shin
Article
41 2022

2022Article

Model-based prediction of acid suppression and proposal of a new dosing regimen of fexuprazan in humansPharmaceuticals, vol. 15, no. 6, pp. 709-709M S Kim; N Lee; A Lee; Y J Chae; S J Chung; Kyeong-Ryoon Lee
Article
40 2022

2022Article

Role of the efflux transporters Abcb1 and Abcg2 in the brain distribution of olaparib in miceEuropean Journal of Pharmaceutical Sciences, vol. 173, pp. 106177-106177Yoo-Kyung Song; Min Ju Kim; M S Kim; J H Lee; S J Chung; J S Song; Y J Chae; Kyeong-Ryoon Lee
Article
39 2022

2022Article

Bioanalysis of alpelisib using liquid chromatography-tandem mass spectrometry and application to pharmacokinetic studyJournal of Analytical Science and Technology, vol. 13, pp. 31-31Seop Lee; M S Kim; Jong Woo Jeong; J W Chae; T S Koo; H J Maeng; S J Chung; Kyeong-Ryoon Lee; Y J Chae
Article
38 2022

2022Article

Sensitive and valid assay for reliable evaluation of drug interactions mediated by human organic anion transporter 1 and 3 using 5-carboxyfluoresceinAnalytical Sciences, vol. 38, no. 10, pp. 1347-1357Kyeong-Ryoon Lee; J E Chang; Y J Chae
Article
37 2022

2022Article

A population PK-PD model of YH4808, a novel P-CAB, and intragastric pH that incorporated negative feedback by increased intragastric pH onto the systemic exposure to YH4808CPT-Pharmacometrics & Systems Pharmacology, vol. 11, no. 9, pp. 1223-1233T K Chung; H A Lee; Kyeong-Ryoon Lee; S B Jang; K S Yu; H Lee
Article
36 2022

2022Research Project

천연물 기반 선도물질 선별 및 최적화 기반기술 확립 = Screening of lead molecules from natural porducts and establishment of flatform for optimization technology연구책임자 : 안경섭 / 사업기간 : 2022.01.01 ~ 2022.12.31
Research Project
35 2022

2022Research Project

고효율 3D 다기능 생체조직기반 유효성 및 안전성 스크리닝 서비스연구책임자 : 이경륜 / 사업기간 : 2022.01.01 ~ 2022.12.31
Research Project
34 2022

2022Article

Findings on in vitro transporter-mediated drug interactions and their follow-up actions for labeling: analysis of drugs approved by US FDA between 2017 and 2021Pharmaceutics, vol. 14, no. 10, pp. 2078-2078Kyeong-Ryoon Lee; J E Chang; J Yoon; H Jin; Y J Chae
Article
33 2022

2022Article

Pharmacokinetics of fluconazole after oral administration to healthy beagle dogsVeterinary Dermatology, vol. 33, no. 6, pp. 509-515Y Choi; Y Koo; T Yun; Y Chae; D Lee; Jong Woo Jeong; Kyeong-Ryoon Lee; H Kim; M P Yang; B T Kang
Article
32 2022

2022Article

Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a systemMolecular Therapy-Nucleic Acids, vol. 28, pp. 353-362Hanseop Kim; Wi-Jae Lee; Chan Hyoung Kim; Yeounsun Oh; L W Gwon; H Lee; W Song; J K Hur; Kyung Seob LimKang Jin Jeong, et al.
Article
31 2021

2021Report

실험동물자원 활용기반 구축 및 지원 사업 = Infra-Building and Services in Biomedical Mouse Resource연구책임자 : 남기환 / 주관부처 : 과학기술정보통신부남기환김형진윤원기원영석; 문옥성; 이기훈서영원; 고영호; 김해림김은경, et al.
Report
30 2021

2021Report

인공지능 등 차세대 기반기술 기반 신약 분야 신규사업 기획연구 = Design New platform for R&D project on Drug Development including AI연구책임자 : 이규선 / 주관부처 : 과학기술정보통신부이규선조성찬김정훈변상원이경륜; 김건호; 송정민김현수
Report
29 2021

2021Article

Development of physiologically based pharmacokinetic model for orally administered fexuprazan in humansPharmaceutics, vol. 13, no. 6, pp. 813-813Y S Jeong; M S Kim; N Lee; A Lee; Y J Chae; S J Chung; Kyeong-Ryoon Lee
Article
28 2021

2021Article

Interplay among conformation, intramolecular hydrogen bonds, and chameleonicity in the membrane permeability and cyclophilin A binding of Mmacrocyclic peptide cyclosporin O derivativesJournal of Medicinal Chemistry, vol. 64, no. 12, pp. 8272-8286D Lee; S Lee; J Choi; Y K Song; Min Ju Kim; D S Shin; M A Bae; Y C Kim; C J Park; Kyeong-Ryoon Lee, et al.
Article
27 2021

2021Article

Population pharmacokinetic method to predict within-subject variability using single-period clinical dataPharmaceuticals, vol. 14, no. 2, pp. 114-114W H Kang; J Y Lee; J W Chae; Kyeong-Ryoon Lee; I H Baek; M S Kim; H M Back; S Jung; C Shaffer; R Savic, et al.
Article
26 2021

2021Article

The development of a functional human small intestinal epithelium model for drug absorptionScience Advances, vol. 7, no. 23, pp. eabh1586-eabh1586Ohman Kwon; Kwang Bo Jung; Kyeong-Ryoon Lee; Ye Seul Son; Hana Lee; Jongjin Kim; Kwangho Kim; Seop Lee; Yoo-Kyung Song; Jaeeun Jung, et al.
Article
25 2021

2021Article

Engineering Yarrowia lipolytica for de novo production of tetraacetyl phytosphingosineJournal of Applied Microbiology, vol. 130, no. 6, pp. 1981-1992Changpyo Han; Min Jeong JangMin Ju Kim; Manho Han; Kyeong-Ryoon Lee; J S Hahn; Jungoh Ahn
Article
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