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Results 1-20 of 45 (Search time: 0.002 seconds).

No. Year Title Type
45 2025

2025Article

Inhibition of breast cancer resistance protein by flavonols: in vitro, in vivo, and in silico implications of the interactionsScientific Reports, vol. 15, pp. 28558-28558Kyeong-Ryoon Lee; M J Kang; Min Ju Kim; Yiseul Im; Hyeon Cheol Jeong; Y J Chae
Article
44 2024

2024Article

Proline-hinged α-helical peptides sensitize gram-positive antibiotics, expanding their physicochemical properties to be used as gram-negative antibioticsJournal of Medicinal Chemistry, vol. 67, no. 3, pp. 1825-1842Y Choi; H W Choe; M Kook; S Choo; T W Park; S Bae; H Kim; J Yang; Woo-Seong Jeong; J Yu, et al.
Article
43 2024

2024Article

Quality by design-based approach for the development of an analytical method for quantifying ponatinib in rat plasmaHeliyon, vol. 10, no. 19, pp. e38637-e38637N Koo; E J Lee; Min Ju Kim; Minjung Park; Kyeong-Ryoon Lee; Y J Chae
Article
42 2024

2024Article

Roles of breast cancer resistance protein and organic anion transporting polypeptide 2B1 in gastrointestinal toxicity induced by SN-38 under inflammatory conditionsToxicology Letters, vol. 394, pp. 57-65A Gulnaz; Kyeong-Ryoon Lee; M J Kang; J E Chang; Y J Chae
Article
41 2024

2024Article

Evaluation of drug blood-brain-barrier permeability using a microfluidic chipPharmaceutics, vol. 16, no. 5, pp. 574-574J Y Yang; D S Shin; Moonkyu Jeong; S S Kim; H N Jeong; B H Lee; K S Hwang; Y Son; Hyeon Cheol Jeong; C H Choi, et al.
Article
40 2024

2024Article

A phase I, open-label, sequential, single-dose clinical trial to evaluate the pharmacokinetic, pharmacodynamic, and safety of IVL3001, a finasteride-based novel long-acting injection for androgenetic alopeciaAdvances in Therapy, vol. 41, no. 7, pp. 2936-2952H Kim; C Ryu; M Lee; Kyeong-Ryoon Lee; J Kim
Article
39 2024

2024Article

Drug interaction-informed approaches to inflammatory bowel disease managementPharmaceutics, vol. 16, no. 11, pp. 1431-1431Kyeong-Ryoon Lee; A Gulnaz; Y J Chae
Article
38 2024

2024Article

Interactions of bosutinib with drug transporters: In vitro and In vivo inhibition of organic cation transporter 2, multidrug and toxin extrusion protein 1, and breast cancer resistance protein by bosutinibBiomedicine & Pharmacotherapy, vol. 178, pp. 117114-117114M J Kang; Min Ju Kim; Y Seol; J E Chag; Kyeong-Ryoon Lee; Y J Chae
Article
37 2024

2024Article

Pharmacokinetic interactions of niclosamide in rats: Involvement of organic anion transporters 1 and 3 and organic cation transporter 2Chemico-Biological Interactions, vol. 390, pp. 110886-110886M J Kang; Min Ju Kim; A Kim; T S Koo; Kyeong-Ryoon Lee; Y J Chae
Article
36 2023

2023Article

Physiologically based pharmacokinetic modelling to predict pharmacokinetics of enavogliflozin, a sodium-dependent glucose transporter 2 inhibitor, in humansPharmaceutics, vol. 15, no. 3, pp. 942-942M S Kim; Yoo-Kyung Song; J S Choi; H Y Ji; E Yang; J S Park; H S Kim; Min Joo KimIn Kyung Cho; S J Chung, et al.
Article
35 2023

2023Article

A mechanism-based understanding of altered drug pharmacokinetics by gut microbiotaJournal of Pharmaceutical Investigation, vol. 53, pp. 73-92A Gulnaz; J E Chang; H J Maeng; K H Shin; Kyeong-Ryoon Lee; Y J Chae
Article
34 2023

2023Article

Strong inhibition of organic cation transporter 2 by flavonoids and attenuation effects on cisplatin-induced cytotoxicityChemico-Biological Interactions, vol. 379, pp. 110504-110504K H Shin; Kyeong-Ryoon Lee; M J Kang; Y J Chae
Article
33 2023

2023Article

A preliminary study of pharmacokinetics and pharmacodynamics of oral fingolimod in dogsin Vivo, vol. 37, no. 5, pp. 2128-2133T Yun; Jong Woo Jeong; Y Koo; Y Chae; D Lee; H Kim; S Kim; M P Yang; Kyeong-Ryoon Lee; B T Kang
Article
32 2022

2022Article

Role of the efflux transporters Abcb1 and Abcg2 in the brain distribution of olaparib in miceEuropean Journal of Pharmaceutical Sciences, vol. 173, pp. 106177-106177Yoo-Kyung Song; Min Ju Kim; M S Kim; J H Lee; S J Chung; J S Song; Y J Chae; Kyeong-Ryoon Lee
Article
31 2022

2022Article

Integration of a physiologically based pharmacokinetic and pharmacodynamic model for tegoprazan and its metabolite: application for predicting food effect and intragastric pH alterationsPharmaceutics, vol. 14, no. 6, pp. 1298-1298H C Jeong; M G Kim; Z Wei; Kyeong-Ryoon Lee; J Lee; I S Song; K H Shin
Article
30 2022

2022Article

Model-based prediction of acid suppression and proposal of a new dosing regimen of fexuprazan in humansPharmaceuticals, vol. 15, no. 6, pp. 709-709M S Kim; N Lee; A Lee; Y J Chae; S J Chung; Kyeong-Ryoon Lee
Article
29 2022

2022Article

Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a systemMolecular Therapy-Nucleic Acids, vol. 28, pp. 353-362Hanseop Kim; Wi-Jae Lee; Chan Hyoung Kim; Yeounsun Oh; L W Gwon; H Lee; W Song; J K Hur; Kyung Seob LimKang Jin Jeong, et al.
Article
28 2022

2022Article

Findings on in vitro transporter-mediated drug interactions and their follow-up actions for labeling: analysis of drugs approved by US FDA between 2017 and 2021Pharmaceutics, vol. 14, no. 10, pp. 2078-2078Kyeong-Ryoon Lee; J E Chang; J Yoon; H Jin; Y J Chae
Article
27 2022

2022Article

Bioanalysis of alpelisib using liquid chromatography-tandem mass spectrometry and application to pharmacokinetic studyJournal of Analytical Science and Technology, vol. 13, pp. 31-31Seop Lee; M S Kim; Jong Woo Jeong; J W Chae; T S Koo; H J Maeng; S J Chung; Kyeong-Ryoon Lee; Y J Chae
Article
26 2022

2022Article

A population PK-PD model of YH4808, a novel P-CAB, and intragastric pH that incorporated negative feedback by increased intragastric pH onto the systemic exposure to YH4808CPT-Pharmacometrics & Systems Pharmacology, vol. 11, no. 9, pp. 1223-1233T K Chung; H A Lee; Kyeong-Ryoon Lee; S B Jang; K S Yu; H Lee
Article
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