Orphan Disease Therapeutic Target Research Center (희귀난치질환표적연구센터)
Results 1-20 of 60 (Search time: 0.002 seconds).
No. | Year | Title | Type |
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60 | 2025 | 2025Article Discovery of novel WRN inhibitors for treating MSI-H colorectal cancersBioorganic & Medicinal Chemistry Letters, vol. 120, pp. 130141-130141Byul Moon; A Go; Seulki Park; H J Kim; D An; J Kim; J Y Lee; Jeong Hoon Kim; J Y Hwang; Jung Ae Kim |
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59 | 2025 | 2025Article Design and evaluation of anaplastic lymphoma kinase degraders using a covalent fumarate handleBioorganic & Medicinal Chemistry Letters, vol. 117, pp. 130075-130075N Yu; Ji-Eun Lee; S Park; S K Yun; D H Ryu; Jung Ae Kim; Jeong Hoon Kim; J Y Hwang |
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58 | 2025 | 2025Article Discovery of a novel molecular glue degrader targeting GSPT1/2 with a non-IMiD based CRBN binderEuropean Journal of Medicinal Chemistry, vol. 291, pp. 117642-117642Seulki Park; A D Takwale; Ji-Eun Lee; N Yu; Y H Kim; J Y Lee; Y H Cho; Jin Hwa Cho; Jeong Hee Moon; Gaseul Lee, et al. |
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57 | 2024 | 2024Article Histone lysine methylation modifiers controlled by protein stabilityExperimental and Molecular Medicine, vol. 56, no. 10, pp. 2127-2144Sungryul Park; Jin Hwa Cho; Jeong Hoon Kim; Jung Ae Kim |
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56 | 2023 | 2023Article Design of hypoxia responsive CRISPR-Cas9 for target gene regulationScientific Reports, vol. 13, pp. 16763-16763Yan An; C S Talwar; Kwang Hyun Park; Woo-Chan Ahn; Su-Jin Lee; Seong Ryeong Go; Jin Hwa Cho; Do Yon Kim; Yong-Sam Kim; S Cho, et al. |
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55 | 2023 | 2023Article Hypoxia stabilizes SETDB1 to maintain genome stabilityNucleic Acids Research, vol. 51, no. 20, pp. 11178-11196Sungryul Park; Jin Hwa Cho; Jong-Hwan Kim; Mijin Park; Seulki Park; Seon-Young Kim; Seon-Kyu Kim; K Kim; Sung Goo Park; Byoung Chul Park, et al. |
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54 | 2023 | 2023Article Discovery of pan-IAP degraders via a CRBN recruiting mechanismEuropean Journal of Medicinal Chemistry, vol. 245, no. 2, pp. 114910-114910Seulki Park; D Kim; W Lee; Jin Hwa Cho; Sungyoung Kim; Ga Seul Lee; Jeong Hee Moon; Jung Ae Kim; J D Ha; Jeong Hoon Kim, et al. |
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53 | 2023 | 2023Article CDK9 inhibitors downregulate DKK1 expression to suppress the metastatic potential of HCC cellsGenes & Genomics, vol. 45, no. 3, pp. 285-293Mijin Park; Jin Hwa Cho; Byul Moon; Jeong Hoon Kim; Jung Ae Kim |
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52 | 2022 | 2022Article Synergistic antitumor activity of sorafenib and MG149 in hepatocellular carcinoma cellsBMB Reports, vol. 55, no. 10, pp. 506-511Byul Moon; Mijin Park; Seung-Hyun Cho; K M Kim; H R Seo; Jeong Hoon Kim; Jung Ae Kim |
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51 | 2022 | 2022Article Downregulation of SETD5 suppresses the tumorigenicity of hepatocellular carcinoma cellsMolecules and Cells, vol. 45, no. 8, pp. 550-563Mijin Park; Byul Moon; Jong-Hwan Kim; Seung-Jin Park; Seon-Kyu Kim; K Park; J Kim; Seon-Young Kim; Jeong Hoon Kim; Jung Ae Kim |
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50 | 2022 | 2022Article Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse modelBioorganic Chemistry, vol. 127, pp. 105923-105923A D Takwale; E Y Kim; Y Jang; D H Lee; S Kim; Y Choi; J H Kim; D Y Lee; Y Kim; S M Lee, et al. |
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49 | 2022 | 2022Article Artificial intelligence-based identification of octenidine as a Bcl-xL inhibitorBiochemical and Biophysical Research Communications, vol. 588, pp. 97-103A R N Bui; H Son; Seulki Park; Sohee Oh; Jin Sik Kim; Jin Hwa Cho; Hye-Jin Hwang; Jeong Hoon Kim; G S Yi; Seung-Wook Chi |
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48 | 2022 | 2022Article Novel GPR43 agonists exert an anti-Inflammatory effect in a colitis modelBiomolecules & Therapeutics, vol. 30, no. 1, pp. 48-54Bioh Park; Jong Soon Kang; S Paudel; Sung Goo Park; Byoung Chul Park; S B Han; Y S Kwak; Jeong Hoon Kim; Sunhong Kim |
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47 | 2021 | 2021Article Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathwaysCell Death and Differentiation, vol. 28, no. 3, pp. 900-914Jin Hwa Cho; Kidae Kim; Sung Ah Kim; Seongryul Park; Bi-Oh Park; Jong Hwan Kim; Seon-Young Kim; M J Kwon; M H Han; S B Lee, et al. |
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46 | 2021 | 2021Article Phosphorylation of REPS1 at Ser709 by RSK attenuates the recycling of Transferrin receptorBMB Reports, vol. 54, no. 5, pp. 272-277Seong Heon Kim; Jin Hwa Cho; Bi-Oh Park; Byoung Chul Park; Jeong Hoon Kim; Sung Goo Park; Sunhong Kim |
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45 | 2021 | 2021Article The short-chain fatty acid receptor GPR43 modulates YAP/TAZ via RhoAMolecules and Cells, vol. 44, no. 7, pp. 458-467Bi-Oh Park; Seong Heon Kim; Jong Hwan Kim; Seon-Young Kim; Byoung Chul Park; S B Han; Sung Goo Park; Jeong Hoon Kim; S Kim |
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44 | 2021 | 2021Article Long-term depletion of Cereblon induces mitochondrial dysfunction in cancer cellsBMB Reports, vol. 54, no. 6, pp. 305-310Seulki Park; K Kim; Keeok Haam; Hyun Seung Ban; Jung Ae Kim; Byoung Chul Park; Sung Goo Park; Sunhong Kim; Jeong Hoon Kim |
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43 | 2021 | 2021Article Sjogren syndrome antigen B regulates LIN28-let-7 axis in Caenorhabditis elegans and humanBiochimica et Biophysica Acta-Gene Regulatory Mechanisms, vol. 1864, pp. 194684-194684Seong Heon Kim; Bi-Oh Park; Kidae Kim; Byoung Chul Park; Sung Goo Park; Jeong Hoon Kim; S Kim |
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42 | 2020 | 2020Article Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimerasEuropean Journal of Medicinal Chemistry, vol. 208, pp. 112769-112769A D Takwale; Seung-Hyun Jo; Y U Jeon; H S Kim; C H Shin; H K Lee; S Ahn; C O Lee; J D Ha; Jeong Hoon Kim, et al. |
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41 | 2020 | 2020Article The tumor suppressor, p53, negatively regulates non-canonical NF-κB signaling through miRNA-induced silencing of NF-κB-inducing kinaseMolecules and Cells, vol. 43, no. 1, pp. 23-33Hanbit Jang; Seulki Park; J Kim; Jong Hwan Kim; Seon-Young Kim; S Cho; Sung Goo Park; Byoung Chul Park; Sunhong Kim; Jeong Hoon Kim |
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